Your DNA could predict your heart attack risk – but does knowing help?
NCT ID NCT06542432
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 37 times
Summary
This study looks at whether giving people a combined genetic and lifestyle risk score for heart disease helps doctors make better decisions. About 1,000 adults with moderate risk will be randomly assigned to receive their score or not. Researchers will track if those who get their score are more likely to start cholesterol medication or have better cholesterol levels.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that giving patients a personalized genetic risk score helps doctors start cholesterol-lowering drugs earlier, potentially preventing heart attacks.
What could go wrong
This is an observational study, not a treatment trial. It only measures if risk information changes behavior, not whether it actually reduces heart disease. Results may not apply to everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.