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Gene test could predict heart attack and stroke risk

NCT ID NCT06855394

Knowledge-focused Sponsor: University of Florida Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines whether a common gene variation (CYP2C19) influences the long-term risk of serious heart and blood vessel events, such as heart attacks, strokes, and limb problems, in people with vascular disease. Researchers will analyze genetic and health data from 13,000 patients at the University of Florida. The goal is to better understand how genetics affect treatment outcomes, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 13,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2011

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with systemic atherosclerosis.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients aged ≥18 years with available CYP2C19 genotyping results obtained within the predefined period. Exclusion Criteria: * Absence of CYP2C19 genotyping results obtained within the predefined period.

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Conditions

The condition(s) this trial relates to.

atherosclerosis cardiovascular disorder coronary artery disorder coronary atherosclerosis heart disorder peripheral arterial disease stroke disorder venous thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atherosclerosis of arteries of the extremities, unspecified Atherosclerosis of coronary artery Atherosclerotic vascular disease Coronary arterial disease (CAD) Heart diseases Stroke Venous thromboembolic disease

Contacts and locations

Locations

  • UF Health

    Gainesville, Florida, 32608, United States

  • UF Health

    Jacksonville, Florida, 32209, United States

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