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New nerve block could cut opioid use after heart surgery

NCT ID NCT06077422

First seen Feb 28, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This study tests whether a nerve block given before heart surgery can reduce pain and the need for opioid painkillers afterward. About 150 adults having certain heart surgeries will receive either a long-acting or standard form of the numbing drug bupivacaine. Researchers will track how much pain medication patients need in the first five days after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rutgers RWJMS

    New Brunswick, New Jersey, 08903, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine (as liposomal or standard injection)

What this could lead to

If it works, this could offer a better way to manage pain after heart surgery, reducing the need for strong painkillers like opioids.

What could go wrong

This is a small pilot study, so results may not apply to everyone. The nerve block may not provide enough pain relief, and there are risks like infection or nerve damage.

Conditions

The condition(s) this trial relates to.

heart disorder opioid abuse Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.