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Why do south asians have higher heart disease risk? major study seeks answers

NCT ID NCT01207167

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study follows over 2,300 South Asian adults in the US to understand why they have high rates of heart disease and stroke, even without traditional risk factors. Participants are aged 40-84 and have no prior heart events. Researchers will track heart scans, diabetes, and other health markers over several years to identify new risk factors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal new risk factors for heart disease in South Asians, leading to better prevention strategies for this high-risk group.
What could go wrong
This is an observational study, not a treatment trial. It may not identify clear causes, and findings might not apply to all South Asians or other ethnic groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,314 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Sep 2010

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

South Asians (individuals from India, Pakistan, Nepal, Bangladesh, and Sri Lanka) adults between the ages of 40 and 84 years without cardiovascular disease living in the San Francisco Bay Area, Chicago Area, or New York City Area.

Ages

40 to 84 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * South Asian ancestry defined by having at least 3 grandparents born in one of the following countries: India, Pakistan, Bangladesh, Nepal, or Sri Lanka * age between 40 and 84 years. Exclusion Criteria: * Physician diagnosed heart attack, stroke or transient ischemic attack (TIA), heart failure, or angina (or use of nitroglycerin) * Current atrial fibrillation * Past history of cardiovascular procedures (coronary artery bypass graft (CABG) Surgery, angioplasty, valve replacement, pacemaker or defibrillator implantation, or any surgery on the heart or arteries) * Active treatment for cancer * Life expectancy less than 5 years due to serious medical illness * Impaired cognitive ability as judged by the reviewer * Plans to move out of the study region in next 5 years * Weight greater than 300 pounds * Living in a nursing home or on a waiting list * Unable to speak/read/write English, Hindi, Urdu, or Bangla

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Conditions

The condition(s) this trial relates to.

atherosclerosis cardiovascular disorder coronary artery disorder Coronary Disease heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atherosclerosis Cardiovascular diseases Coronary artery disease Coronary disease Heart diseases

Contacts and locations

Locations

  • New York University

    New York, New York, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • University of California, San Francisco

    San Francisco, California, 94115, United States

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