HEAD AND NECK NEOPLASMS

This study tested whether a daily oral pill (afatinib) could work better than a standard intravenous chemotherapy (methotrexate) for people with advanced head and neck cancer that had stopped responding to initial platinum-based treatments. It involved 340 patients and aimed to s…

This large, completed Phase 3 trial tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation treatment works better than chemoradiation alone for people with locally advanced head and neck cancer. The study enrolled 804 patients to see if the combinat…

This study compared two standard treatment approaches for advanced head and neck cancer that had spread to lymph nodes. It tested whether performing neck surgery before combined chemotherapy and radiation could reduce severe treatment side effects and improve quality of life, wit…

This study tested whether combining two existing cancer drugs, pembrolizumab and cetuximab, could help control advanced head and neck cancer that had returned or spread. It involved 78 patients at four US cancer centers, grouped based on their prior treatments. The main goal was …

This study tested whether using lower radiation doses to healthy neck lymph nodes could reduce long-term side effects while still preventing cancer recurrence. It involved 300 adults with head and neck cancer who were scheduled for curative radiation treatment. Researchers compar…

This study looked back at whether ozone therapy could help patients with painful mouth sores caused by radiation or chemotherapy for head and neck cancer. Thirty-eight patients received professional ozone treatments and used a special ozonated oil at home. Researchers measured if…

This study tested whether a short exercise program before starting cancer treatment could help patients with head and neck cancer. Forty-seven patients were split into two groups: one did exercise training for at least two weeks before chemo and radiation, while the other receive…

This study tested two non-drug treatments for painful mouth sores caused by cancer therapy. Forty adult cancer patients with moderate to severe sores were randomly assigned to receive either laser light therapy or ozone gas therapy daily for five days. Researchers measured which …

This study tested whether providing active nutritional support could help head and neck cancer patients receiving radiotherapy. It aimed to see if better nutrition could reduce the painful mouth sores (mucositis) that are a common and debilitating side effect of treatment. The go…

This study tested whether real acupuncture is better than fake acupuncture at helping head and neck cancer patients feel less tired and maintain better blood cell counts during combined chemotherapy and radiation. 34 adult patients were randomly assigned to receive either real or…

This study tested a new 3D imaging method to help surgeons plan operations for children with head/neck tumors or birth defects. Researchers used a special 10-minute MRI scan on 7 children aged 1-5 to create detailed maps of delicate nerves in the face and neck. The goal was to se…