HEAD AND NECK NEOPLASMS

This study tested a new oral drug, afatinib, against a standard chemotherapy, methotrexate, in 340 people with advanced head and neck cancer that had returned or spread and stopped responding to platinum-based treatment. The goal was to see which drug worked better at slowing can…

This study tested a combination of two drugs, pembrolizumab and cetuximab, in 78 adults with advanced head and neck cancer that had spread or come back. The goal was to see if the combo could shrink tumors or slow the disease. Patients were grouped based on whether they had tried…

This study tested a combination of two drugs, atezolizumab and bevacizumab, in 33 adults with advanced head and neck cancer that had already been treated with platinum-based chemotherapy. The goal was to see if the combo could shrink or control tumors. The approach aims to boost …

This study looked at people with advanced head and neck cancer that had spread to lymph nodes. It compared two treatments: having neck surgery first followed by chemo-radiation, versus chemo-radiation alone. The goal was to see if the surgery could reduce side effects and improve…

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation could help people with advanced head and neck cancer live longer without their disease getting worse. About 800 participants were randomly assigned to receive either pembrolizumab plu…

This study tested whether ozone therapy can help with painful mouth sores caused by radiation and chemotherapy for head and neck cancer. 38 patients used a combination of in-office ozone gas treatments and at-home ozonated oil. The goal was to reduce soreness, pain, and improve e…

This study tested two treatments—laser therapy and ozone gas—for painful mouth sores caused by cancer treatment. Forty adults with head/neck or blood cancers received one of the two treatments daily for five days. Researchers measured soreness, pain, and quality of life to see wh…

This study looked at whether active nutritional support can lower the chance of painful mouth sores (mucositis) and improve quality of life in people with head and neck cancer who are getting radiation therapy. 47 newly diagnosed adults took part. Researchers tracked weight and b…

This study looked at whether a short exercise program before chemoradiotherapy helps people with head and neck cancer maintain their physical abilities. 47 adults participated, with half doing supervised exercises for at least 2 weeks before treatment. The goal was to see if exer…

This study tested whether giving a lower dose of radiation to the neck area in people with head and neck cancer could reduce side effects and improve quality of life after treatment. About 300 patients with certain throat or voice box cancers took part. The goal was to see if thi…

This study tested whether adding manual acupuncture to standard chemoradiation helps head and neck cancer patients. 34 adults received either real or sham acupuncture three times a week for seven weeks. Researchers measured white blood cell counts, fatigue levels, and quality of …

This completed study tested a new way to create 3D models of nerves in the head and neck area using MRI scans. Seven children aged 1 to 5 with tumors or birth defects took part. The goal was to help surgeons plan operations more precisely by seeing exactly where important nerves …

This study tested whether a special PET scan (18F-FMISO) can measure low oxygen levels (hypoxia) in head and neck tumors. Sixteen adults with head and neck cancer received the scan before starting radiation therapy. Researchers then checked if the scan results matched treatment o…