HEAD AND NECK NEOPLASMS
Clinical trials for HEAD AND NECK NEOPLASMS explained in plain language.
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New pill targets cancer's genetic weak spot in 15 tumor types
Disease control OngoingThis study tests an experimental drug called entrectinib in people with advanced solid tumors that have certain gene changes (NTRK, ROS1, or ALK). The drug aims to shrink or control the cancer by blocking signals that help it grow. About 534 adults with various cancers, including…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 26, 2026 07:26 UTC
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Supercharged immune cells take on tough cancers
Disease control OngoingThis early-phase study tests a new treatment called KSQ-001EX for people with advanced solid tumors like melanoma, lung, or head and neck cancers. The treatment uses a patient's own immune cells, which are modified in a lab to work better against cancer. The main goal is to see i…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 07:24 UTC
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Immunotherapy before and after surgery shows promise for head and neck cancer
Disease control OngoingThis study tests whether adding the immunotherapy drug pembrolizumab before and after surgery can help people with advanced head and neck cancer stay cancer-free longer. About 714 participants will receive either pembrolizumab plus standard radiation (with or without chemo) or ra…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 26, 2026 07:23 UTC
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Smart drug targets HER2 cancers in new trial
Disease control OngoingThis study tests an experimental drug called disitamab vedotin in people with advanced head and neck, lung, endometrial, or ovarian cancers that have a marker called HER2. The drug is designed to stick to cancer cells and kill them. About 120 participants will receive the drug ev…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: PHASE2 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 26, 2026 07:21 UTC
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Amazonian tree oil could soothe radiation mouth pain in cancer patients
Symptom relief OngoingThis early-stage study tests a mouthwash made from copaiba, a natural oil from the Amazon, to see if it can safely prevent or treat painful mouth sores caused by radiation therapy. About 20 adults with head and neck cancer will use the mouthwash during their radiation treatment. …
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: PHASE1 • Sponsor: Instituto Nacional de Cancer, Brazil • Aim: Symptom relief
Last updated May 26, 2026 07:33 UTC
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Robotic surgery vs. radiation: which is better for throat cancer patients' quality of life?
Symptom relief OngoingThis study compares two treatments for early-stage oropharyngeal (throat) cancer: robotic surgery or radiation therapy. The goal is to see which approach leads to better swallowing function and overall quality of life. About 138 patients will be randomly assigned to one of the tw…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: NA • Sponsor: Christian von Buchwald • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Cancer patients' smoking habits tracked after radiation
Knowledge-focused OngoingThis study follows 100 head and neck or lung cancer patients who smoke or used to smoke. Researchers want to see what helps them stay away from cigarettes after they finish radiation or chemoradiation. Patients are checked at 1, 6, and 12 months after treatment ends. The goal is …
Matched conditions: HEAD AND NECK NEOPLASMS
Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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Online prep program for head and neck surgery pulled before starting
Knowledge-focused TerminatedThis study aimed to see if a personalized online education program could help patients and caregivers feel more prepared before and after major head and neck surgery. It also hoped to reduce hospital readmissions and unplanned visits. However, the study was withdrawn before any p…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC