Head and neck neoplasms
Clinical trials for Head and neck neoplasms explained in plain language.
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New hope for advanced HER2 cancers? drug trial launches
Disease control Not yet recruitingThis early-phase study tests a drug called zanidatamab in 10 adults with advanced HER2-positive solid tumors (like endometrial, bladder, or pancreatic cancer) that have worsened after at least one prior treatment. Participants receive the drug by IV every two weeks. The main goal…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase 2 • Sponsor: Haihua Yuan • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New drug targets hard-to-treat cancers in early trial
Disease control Not yet recruitingThis study tests a drug called Trastuzumab Rezetecan in 15 adults with advanced solid tumors that have the HER2 protein. The goal is to see if the drug can shrink tumors. Participants get the drug by IV every 3 weeks. This is for people whose cancer has worsened after other treat…
Matched conditions: HEAD AND NECK NEOPLASMS
Phase 2 • Sponsor: Haihua Yuan • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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AI reads tumor slides to match cancer patients with trials
Diagnosis Not yet recruitingMany cancer trials require patients to have specific molecular markers, so researchers test large numbers of people to find the few who qualify. This study evaluates FATHOM, an AI system that reads clinical trial records and routine tumor slides to predict which patients carry th…
Matched conditions: HEAD AND NECK NEOPLASMS
Sponsor: Harvard Medical School (HMS and HSDM) • Aim: Diagnosis
Last updated Sep 13, 2026 00:00 UTC
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Can light be the new shield against radiation mouth sores?
Prevention Not yet recruitingThis pilot study tests two light therapy devices—one placed inside the mouth and one outside—to prevent and treat painful mouth sores caused by radiation therapy. Sixty adults with oral cavity or oropharynx cancer will receive light sessions twice a week for prevention, then thre…
Matched conditions: HEAD AND NECK NEOPLASMS
Sponsor: Centre Paul Strauss • Aim: Prevention
Last updated Jun 27, 2026 13:02 UTC
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Shorter radiation course tested for advanced head and neck cancer
Symptom relief Not yet recruitingResearchers compare two palliative radiation schedules for people with incurable head and neck cancer. The standard Split Course takes several weeks and often causes hard-to-tolerate side effects. The study tests whether a shorter Quad Shot regimen can shrink tumors and ease symp…
Matched conditions: HEAD AND NECK NEOPLASMS
Sponsor: Instituto Nacional de Cancerologia, Columbia • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Can a simple phone call after the ER get cancer patients treated faster?
Knowledge-focused Not yet recruitingThis pilot study will test whether trained community health navigators can help head and neck cancer patients get diagnosed and treated faster after an emergency room visit. The navigators will call or text patients to help with barriers like transportation, insurance, or housing…
Matched conditions: HEAD AND NECK NEOPLASMS
Sponsor: University of Tennessee • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC