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Pre-Treatment workouts may boost strength in head and neck cancer patients

NCT ID NCT05418842

Symptom relief Sponsor: Associacao de Investigacao de Cuidados de Suporte em Oncologia Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a short exercise program before chemoradiotherapy helps head and neck cancer patients maintain physical function. 47 adults with head and neck cancer were randomly assigned to either an exercise prehabilitation group or usual care. The exercise program lasted at least 2 weeks, and researchers measured walking ability, muscle strength, and quality of life before and after treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

47 people

The number who actually took part.

Started

May 2021

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years old; * Histologically confirmed HNSCC located on the oral cavity, larynx, oropharynx, hypopharynx, nasopharynx or in lymph nodes from an unknown primary tumor (stage I-IV); * Proposed for concomitant chemoradiotherapy with curative intent; * Date of treatment beginning ≥2 weeks from baseline assessment; * ECOG-Performance Status 0-1. Exclusion Criteria: * Completion of previous anticancer treatment within less than a year; * Uncontrolled hypertension, cardiac or pulmonary disease; * Contraindications to exercise training; * Inability to provide informed consent; * Expected inability to fulfil the proposed schedule.

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Conditions

The condition(s) this trial relates to.

head and neck neoplasm Head and Neck Neoplasms head and neck squamous cell carcinoma Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck neoplasms

Contacts and locations

Locations

  • Centro Hospitalar Vila Nova de Gaia/Espinho

    Vila Nova de Gaia, Porto District, 4434-502, Portugal

  • Instituto Português de Oncologia do Porto (IPO-Porto)

    Porto, Região, Portugal

  • Liga Portuguesa Contra o Cancro - Núcleo Regional do Norte (LPCC-NRN)

    Porto, Portugal

  • University of Aveiro

    Aveiro, 3810-193, Portugal

  • University of Maia

    Maia, Porto District, 4475-690, Portugal

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