ENDOMETRIOSIS

This study tests a less invasive surgery called laparoscopic sclerotherapy for ovarian cysts (endometriomas) caused by endometriosis. The goal is to see if this approach better protects a woman's egg supply (ovarian reserve) compared to the standard surgery that removes the entir…

This study aims to develop a non-invasive test for endometriosis using AI-enhanced ultrasound and biomarkers from blood, saliva, urine, and tissue. It involves 365 women aged 18-45 with suspected or confirmed endometriosis. The goal is to replace the need for surgery to diagnose …

This study tests whether a total-body PET/CT scan can spot endometriosis without needing surgery. About 30 women with suspected endometriosis will get two scans using special tracers that highlight bleeding and scarring. The scan results will be compared to findings from their pl…

This study tests a new device called Hyivy that people with endometriosis can use at home to manage chronic pelvic pain without hormones. About 20 adults with endometriosis and ongoing pelvic pain will use the device and report their pain levels. The goal is to see if the device …

This study tests whether up to 9 sessions of electroacupuncture can reduce pelvic pain in women with suspected endometriosis who are scheduled for a diagnostic laparoscopy. Researchers will measure pain levels, quality of life, and pain medication use. The goal is to find a non-d…

This study tests a new drug called HMI-115 to see if it can reduce pain in women with moderate to severe endometriosis. About 540 women aged 18-49 with surgically confirmed endometriosis will receive either the drug or a placebo for 24 weeks, with an optional 28-week extension. T…

This study compares two laparoscopic hysterectomy methods (total removal vs partial removal of the uterus) in 500 women with benign conditions like fibroids or endometriosis. The goal is to see which approach leads to better quality of life and fewer complications over three year…

This study will test whether following a Mediterranean diet can improve quality of life and reduce pain in women with endometriosis, a chronic inflammatory condition. Researchers plan to enroll 104 women aged 18-45 who have been diagnosed with endometriosis and have at least mode…

This study looks at how well a daily pill called relugolix combination therapy works for reducing endometriosis-related pain over 24 weeks in everyday medical practice. About 33 women aged 18-50 with confirmed endometriosis and moderate to severe pain will take part. The goal is …

This study tests a portable device called ActiTENS mini that uses mild electrical pulses to relieve chronic pelvic pain in women with endometriosis. About 208 women will use the device daily for 30 minutes over three 3-month periods, comparing different stimulation strengths. The…

This study tests whether psychological support—individual therapy, group sessions, or a mix—can improve quality of life and reduce anxiety in women with endometriosis. Forty participants will be randomly assigned to one of four groups, including a no-intervention control. The goa…

This study tests whether a 10-week virtual mindfulness program can improve quality of life for 124 people with endometriosis-related chronic pelvic pain. Participants will attend online workshops and complete questionnaires. The goal is to see if this accessible, drug-free approa…

This study tests whether magnetic stimulation using a 'Tesla chair' can reduce pain in women with endometriosis whose pain is not controlled by standard treatments. About 30 participants will receive the treatment, and researchers will measure pain changes using a standard pain s…

This study looks at the immune system of 120 women aged 18-40 with chronic pelvic pain that hasn't improved with hormone treatment. Researchers will measure specific immune markers in the blood to see if there is a unique pattern linked to the pain. The goal is to better understa…

This study looks at 98 women with severe endometriosis affecting the bowel who need surgery. Researchers will compare standard transvaginal ultrasound with a newer method—ultrasound done during surgery—to see which better measures the size and depth of the disease. The goal is to…

This study looks at why some women have repeated IVF failure or miscarriages. Researchers will compare uterine tissue and blood samples from 100 women with and without these problems. The goal is to find immune or bacterial differences that may affect pregnancy, paving the way fo…

This study looks at whether certain chemicals in the environment, called persistent organic pollutants (POPs), are linked to how severe endometriosis is. Researchers will measure POP levels in blood samples from 650 women with endometriosis and compare them to their reported symp…

This study looks at whether women with deep endometriosis affecting the bowel have a higher chance of developing colorectal cancer. Researchers will compare gene activity in healthy and endometriosis-affected bowel tissue from 30 women having surgery. The goal is to improve risk …

This study looks at how immune cells and gut bacteria differ in women with endometriosis compared to those without. Researchers will collect tissue, blood, and stool samples from 40 women having surgery. The goal is to find biological markers that could lead to better treatments,…

This study looks at why migraine and endometriosis often happen together in women. Researchers will follow 150 women over several menstrual cycles, tracking symptoms and taking blood samples to measure a molecule called CGRP. The goal is to find differences between women who have…

This study looks for biological markers in the fluid and tissue of the uterus and ovaries in women with moderate to severe endometriosis. The goal is to understand why some women with endometriosis have trouble getting pregnant and to find ways to personalize fertility treatments…

This study explores whether women with endometriosis who use AI tools like ChatGPT to prepare for their doctor visit have better or worse experiences. Researchers will compare satisfaction, trust, and treatment plan follow-through between AI users and non-users. The goal is to un…

This study follows 100 women with deep endometriosis for two years to see if their lesions grow, shrink, or stay the same on ultrasound. Researchers will also track symptoms and quality of life to understand how the disease progresses and whether ultrasound checkups are always ne…

This study aims to grow diaphragm muscle cells in the lab from tissue removed during endometriosis surgery. Researchers will compare these cells to arm muscle cells to find unique features of the diaphragm. This new tool could help develop therapies for neuromuscular diseases lik…

This study tests whether using ultrasound during surgery helps doctors better remove deep endometriosis from the bowel while keeping the bowel wall safe. About 57 women aged 20-60 with bowel endometriosis will take part. The goal is to see if ultrasound measurements during surger…