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Scientists probe immune clues in endometriosis pain

NCT ID NCT07652593

Knowledge-focused Sponsor: Hopital Foch Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares immune cells, specifically natural killer cells, in women with deep endometriosis and those without the condition. Researchers will collect blood, tissue, and vaginal samples from 50 participants to look for differences that might explain the disease. The goal is to better understand the immune system's role in endometriosis and identify potential biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward immune-based biomarkers for diagnosing or understanding endometriosis.
What could go wrong
This is a small, early pilot study that only observes immune cells, not tests a treatment. It may not lead to any direct benefit for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Endometriosis Group * Female participant aged 18 years or older. * Confirmed diagnosis of deep endometriosis by imaging or surgery. * Pelvic pain and/or severe dysmenorrhea (Visual Analog Scale \> 4). * Premenopausal. * No contraceptive or hormonal treatment during the study menstrual cycle. * Affiliated with a health insurance system. * Able and willing to provide written informed consent. * Control Group * Female participant aged 18 years or older. * No diagnosis of endometriosis. * Premenopausal. * No contraceptive or hormonal treatment during the study menstrual cycle. * No chronic pelvic pain or severe dysmenorrhea (Visual Analog Scale \< 4). * Affiliated with a health insurance system. * Able and willing to provide written informed consent. Exclusion Criteria: * Current infection. * Active cancer. * Active autoimmune disease. * Concomitant hormonal treatment. * Pregnancy. * Participant under guardianship or legal protection. * Participant deprived of liberty.

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Conditions

The condition(s) this trial relates to.

endometriosis Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Hôpital Foch

    Suresnes, 92150, France

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