ENDOMETRIAL CANCER

This study tested a combination of three existing drugs (rucaparib, bevacizumab, and atezolizumab) for women with recurrent or progressive endometrial cancer that had stopped responding to prior treatment. The goal was to see if using these drugs together could shrink tumors and …

This study tested the safety of a shorter, more intense schedule of radiation therapy given to the pelvis after surgery for endometrial (uterine) cancer. The main goal was to find the highest dose that could be given safely by carefully tracking side effects reported by both doct…

This study compared two different approaches for removing lymph nodes during surgery for intermediate and high-risk endometrial cancer. Researchers wanted to determine whether removing more lymph nodes from a higher area (above a major artery) provides better cancer staging and o…

This study tested a new combination drug (MK-4280A) to see if it could help people with certain advanced cancers. It involved 163 people with either a type of advanced skin cancer (cSCC) or a type of endometrial cancer that had spread or returned. The goal was to see if the drug …

This study tested a new three-drug combination (afuresertib, sintilimab, and chemotherapy) for people with advanced solid tumors that had stopped responding to prior immunotherapy. The goal was to find a safe, effective dose and see if this combination could help control cancer g…

This first-in-human study tested a new oral drug called RP903 in people with advanced cancers that had stopped responding to standard treatments. The main goals were to find a safe dose and see how the body processes the drug. The study focused on specific cancers, including ovar…

This study tested a much shorter, 5-day course of radiation therapy for women with certain types of advanced uterine cancer who had already had a hysterectomy. Researchers wanted to see if this shorter treatment could control the cancer as well as the traditional 5-6 week course,…

This study tested whether a 12-week home exercise program could improve heart and blood vessel health in women who had finished treatment for early-stage endometrial cancer. Thirty-three participants received exercise equipment, a fitness tracker, and virtual coaching to follow a…

This study tested a type of internal radiation treatment called high-dose-rate brachytherapy for several cancers, including cervical, prostate, and breast cancer. Researchers placed temporary radiation sources directly into or near tumors to deliver a strong, focused dose. The ma…

This study tested whether high-intensity interval training (HIIT) before standard surgery could slow the growth of endometrial cancer. Thirty women with early-stage endometrial cancer completed personalized HIIT workouts before their hysterectomy. Researchers measured changes in …

This early-stage study aimed to find a safe and effective dose of a new drug called TPST-1495, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced solid tumors. It enrolled 89 adults with cancers like colorectal, lung, and head and neck cancer …

This study compared two ways to find the first lymph nodes that cancer might spread to during surgery for early-stage endometrial cancer. Researchers tested a new method where surgeons keep injecting a safe green dye until they can see the tiny drainage channels in real-time. The…

This study tested whether a new support clinic could help women manage symptoms and improve their quality of life after finishing treatment for early-stage breast, cervical, or endometrial cancer. The clinic used an online system where patients could regularly report their sympto…

This study looked at how chemotherapy affects the quality of life for women with stage II or III endometrial cancer. Researchers compared 51 women who received chemotherapy after surgery and radiation to those who received only radiation. The goal was to understand the long-term …

This study tested a new follow-up model for women who completed treatment for gynecologic cancers like ovarian, cervical, or endometrial cancer. It compared standard doctor visits to a program where nurses provided half the check-ups, focusing on emotional support and coaching pa…

This study tested whether adding a drug called aprepitant to the standard two-drug anti-nausea regimen works better to prevent nausea and vomiting caused by a common chemotherapy for gynecologic cancers. It involved 143 women with ovarian, cervical, or other gynecologic tumors wh…

This study aimed to understand if levels of various minerals and metals in the blood differ between healthy women and those with endometriosis, ovarian cancer, or endometrial cancer. Researchers collected a single blood sample from 40 women (10 per group) and used specialized equ…

This study tested two new methods to encourage people at higher risk for hereditary cancers to get recommended genetic testing. Over 800 participants in Michigan were randomly assigned to either use a special website, receive two coaching phone calls, or get standard information.…

This study tested a digital tool designed to help cancer survivors learn about and decide whether to get genetic testing for hereditary cancer risk. Researchers wanted to see if this smart technology was easy to use and if it encouraged more people to get tested. They compared th…

This study compared two different surgical approaches for removing the uterus (hysterectomy) to see if one causes fewer pressure-related complications. Researchers measured pressure changes in the head during surgery in 66 women undergoing either a standard laparoscopic procedure…

This study aims to understand how common a specific protein marker called HER2 is in recurrent advanced endometrial, ovarian, and cervical cancers in Taiwan. Researchers will look back at the medical records and tissue samples of about 509 patients to see how many have high level…

This study observed 102 women with ovarian, fallopian tube, or endometrial cancer to understand how standard chemotherapy affects their sense of taste, muscle mass, and nutrition. Patients were assessed before, during, and after six cycles of treatment. The goal was to gather inf…