Exercise boosts heart health in endometrial cancer survivors
NCT ID NCT06534008
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a 12-week program of aerobic and strength exercises could improve heart health and fitness in women who finished treatment for endometrial cancer. Thirty-three survivors in remission took part. They received exercise equipment and a Fitbit, and had heart and fitness tests before and after the program.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Willing and able to provide written informed consent * Willing to comply with study procedures and available for the duration of the study * Fluent in spoken and written English * Women 18 years of age or older * Documented diagnosis of Type I, stage I-IIIc endometrial cancer within the past 5 years * Completion of current cytotoxic treatment for endometrial cancer * Technology access (phone call access, broadband internet, Wi-Fi) for tele coaching * Comfort and willingness to use technology (videoconferencing) throughout the study for coaching * Pass the Physical Activity Readiness Questionnaire (PAR-Q) * Medical clearances given by their primary provider / oncologist (if indicated by the PAR-Q) Exclusion Criteria * Absolute contraindications to exercise (i.e., acute myocardial infarction, severe orthopedic or musculoskeletal limitations) * History of previous myocardial infarction, ischemia, or hemorrhagic stroke * Medically documented history of heart disease including heart valve disease, coronary artery disease, heart failure, peripheral artery disease, aortic disease, pericardial disease, cerebrovascular disease, or deep vein thrombosis * Medical documentation of treatment-resistant hypertension OR taking ≥2 medications to treat hypertension * Medically documented history of cardiovascular disease including (but not limited to): bypass surgery, stent procedures, bypass grafts, or coronary angioplasty * Medically documented or self-reported type 1 diabetes (insulin-dependents) * Prescriptions for or use of semaglutide (GLP-1 agonists) including name brands: Ozempic, Wegovy or Mounjaro * Current or recent (within last 3 months) use of hormone replacement therapy (HRT) * Evidence of recurrent or metastatic disease * Currently performing resistance training ≥2 days per week * Currently exceeding 150 minutes of at least moderate intensity exercise per week * Report of chest pain, shortness of breath, fainting, or angina pectoris * Self-reported history of falling, fall risk * Have physical disability that would limit range of motion through exercises such as sitting, standing and inability to walk one block * Plans to move from the area * Enrolled in another clinical trial or has used of any investigational drugs, biologics, or devices within 30 days prior to study enrollment * Self-reported tobacco use in last 7 days, current smoking, current tobacco use including e-cigarettes and vaping devices * Not suitable for study participation due to other reasons at the discretion of the investigator
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Iowa
Iowa City, Iowa, 52242, United States
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Other studies related to the condition(s) this trial covers.
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