CHRONIC KIDNEY DISEASE (CKD)
Clinical trials for CHRONIC KIDNEY DISEASE (CKD) explained in plain language.
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Breathing workouts boost lung power in kidney transplant kids
Disease control CompletedThis study looked at whether special breathing exercises (respiratory muscle training) can improve lung function and muscle strength in children who have had a kidney transplant. 30 children aged 8-18 who were at least 6 months post-transplant took part. The goal was to see if th…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: Atlas University • Aim: Disease control
Last updated May 26, 2026 03:12 UTC
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New device aims to improve dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 to create a blood vessel connection (fistula) for dialysis in 17 people with advanced chronic kidney disease. The goal was to see if the device is safe and works well for hemodialysis. The study focused on complication rates and whethe…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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New hope for dialysis patients: drug AP301 targets dangerous phosphorus levels
Disease control CompletedThis study tested a new drug called AP301 in 474 adults with kidney failure who are on dialysis and have high phosphorus levels. High phosphorus can cause bone and heart problems. The goal was to see if AP301 lowers phosphorus better than the current standard treatment, sevelamer…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: PHASE3 • Sponsor: Alebund Pharmaceuticals • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New device aims to simplify dialysis access for kidney patients
Disease control CompletedThis study tested a new device called FLEX-1 in 16 adults with advanced chronic kidney disease who need dialysis. The device is used to create a special connection between an artery and a vein (called an arteriovenous fistula) that allows for easier and more reliable dialysis ses…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Real-World data reveals how kidney patients use common drug
Knowledge-focused CompletedThis study looked at how doctors in seven Central Eastern European countries prescribe dapagliflozin for chronic kidney disease in routine care. Researchers reviewed medical records of about 1,090 adults to see who gets the drug and what happens over the next year. The goal was t…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Higher dose of common prostate drug may pose risks for seniors with kidney disease
Knowledge-focused CompletedThis study reviewed health records of 14,000 older adults (66+) with advanced chronic kidney disease who started taking tamsulosin, a drug for prostate problems. Researchers compared those on a higher dose (0.8 mg/day) to those on a lower dose (0.4 mg/day) to see if the higher do…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 26, 2026 03:19 UTC
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Sleep aid trazodone may pose hidden dangers for seniors with kidney trouble
Knowledge-focused CompletedThis study examined over 31,000 older adults (age 66+) with chronic kidney disease to see if starting a higher dose of the sleep medication trazodone (75-150 mg/day) leads to more serious events like hospitalization, emergency visits, or death within 30 days compared to a lower d…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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Doctors' views on inflammation in heart and kidney disease surveyed
Knowledge-focused CompletedThis study surveyed 1,500 heart and kidney specialists in China to learn how they think about inflammation in patients with both heart and kidney disease. The goal was to understand their awareness and use of a blood test called hsCRP, which measures inflammation. No treatments w…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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Virtual agent aims to boost kidney transplant knowledge
Knowledge-focused CompletedThis study tested a computer-based virtual healthcare agent designed to educate people with advanced chronic kidney disease and their caregivers about kidney transplantation. 148 adults from Penn Medicine took part. The goal was to see if the virtual agent could increase their in…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 03:12 UTC
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Can a simple medication check keep kidney patients out of the hospital?
Knowledge-focused CompletedThis study looked at whether carefully reviewing and correcting medication lists for hospitalized patients with chronic kidney disease (CKD) could reduce mistakes and prevent them from being readmitted within 90 days. Over 300 adults with CKD stages 2-5 who took at least three re…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Knowledge-focused
Last updated May 26, 2026 03:03 UTC
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Higher antidepressant dose may raise risks for seniors with kidney disease
Knowledge-focused CompletedThis study looked at over 12,000 older adults (65+) with low kidney function to see if starting a higher dose (10 mg/day) of the antidepressant escitalopram is riskier than a lower dose (5 mg/day). The goal was to compare rates of hospitalization, emergency visits, or death withi…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Study reveals hidden dangers of common anxiety drug in seniors with kidney issues
Knowledge-focused CompletedThis study looked at over 12,000 older adults (age 66+) with low kidney function who started taking lorazepam, a common anxiety medication. Researchers compared those taking higher doses (more than 1 mg per day) to those on lower doses (0.5-1 mg per day) to see if the higher dose…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Kidney patients on higher drug dose face greater short-term risks?
Knowledge-focused CompletedThis study checked whether older adults (65+) with advanced chronic kidney disease who start a higher dose of the drug pramipexole have more hospital visits or deaths within 30 days compared to those on a lower dose. Researchers looked at health records of 1,100 people in Ontario…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Kidney patients warned: higher antidepressant dose may raise hospital risk
Knowledge-focused CompletedThis study analyzed health records of nearly 7,000 older adults (65+) with low kidney function who started taking the antidepressant sertraline. Researchers compared those on a 50 mg daily dose to those on 25 mg to see if the higher dose led to more hospital visits, emergency dep…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Higher antidepressant dose may be risky for seniors with kidney issues
Knowledge-focused CompletedThis study examined the safety of starting citalopram at 20 mg/day versus 10 mg/day in adults aged 65 and older with reduced kidney function. Researchers analyzed health records from over 7,000 participants to see if the higher dose increased the risk of hospitalization, emergenc…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC