Chronic kidney disease (CKD)
Clinical trials for Chronic kidney disease (CKD) explained in plain language.
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Sitting less, living better: new study targets kidney health
Disease control OngoingThis study tests a program to help Black adults with chronic kidney disease (CKD) reduce their daily sitting time. Half of the 40 participants will receive support to sit less, while the other half will get general CKD education. The goal is to see if cutting down on sitting can …
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Could a new drug shield hearts and kidneys in overweight people?
Disease control OngoingThis phase 3 trial is testing whether the drug retatrutide can lower the chance of serious heart problems (like heart attacks and strokes) and slow kidney disease in 10,000 overweight adults who already have heart or kidney disease. Participants receive either retatrutide or a pl…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase 3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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New dialysis technique tested for better fluid control in kidney patients
Disease control By invitation onlyThis study compares two types of dialysis in 64 adults with end-stage kidney disease. One group gets standard hemodialysis, the other gets hemodiafiltration, which uses both diffusion and convection to remove waste. The main goal is to see if hemodiafiltration leads to less weigh…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Services Institute of Medical Sciences, Pakistan • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New antibody drug could open door to kidney transplants for Hard-to-Match patients
Disease control OngoingThis study tests a drug called vonsetamig in 43 people with chronic kidney disease who are on dialysis and have very high levels of anti-HLA antibodies, making it nearly impossible to find a matching kidney donor. The drug aims to safely lower these antibodies so that a kidney tr…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Phase 1/2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Higher domperidone doses under scrutiny for older kidney patients
Knowledge-focused OngoingResearchers are examining health records to see whether older adults with advanced chronic kidney disease who start domperidone at 30 mg per day or more face a higher 30-day risk of hospitalization, emergency visits, or death compared with those taking lower doses. The study draw…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Higher antidepressant dose may raise risks for seniors with weak kidneys
Knowledge-focused OngoingThis completed study looked at nearly 7,000 older adults (65+) with low kidney function who started taking the antidepressant sertraline. Researchers compared the safety of a 50 mg daily dose versus a 25 mg daily dose, tracking hospital visits, emergency department visits, or dea…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Higher dose of common drug may raise hospital risk for seniors with kidney trouble
Knowledge-focused OngoingThis completed study looked at 1,100 older adults (65+) with advanced chronic kidney disease who started taking pramipexole, a drug for restless legs or Parkinson's. Researchers compared a very low starting dose (0.125 mg/day) to slightly higher doses (0.25 or 0.375 mg/day) to se…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Higher antidepressant dose may pose risks for seniors with weak kidneys
Knowledge-focused OngoingThis study looked at over 7,000 older adults (65+) with reduced kidney function who started taking the antidepressant citalopram. Researchers compared a 20 mg/day dose to a 10 mg/day dose to see if the higher dose increased the risk of serious events like hospitalization, emergen…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Higher lorazepam doses may be riskier for seniors with weak kidneys
Knowledge-focused OngoingThis completed study looked at over 12,000 older adults (66+) with low kidney function who started taking lorazepam. Researchers compared higher doses (1-4 mg/day) to lower doses (0.5-1 mg/day) to see if there was a greater risk of hospitalization, emergency visits, or death with…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Antidepressant dose matters for seniors with kidney trouble
Knowledge-focused OngoingThis study looked at over 12,000 older adults (age 66+) with low kidney function who started taking the antidepressant escitalopram. Researchers compared the safety of a 10 mg daily dose versus a 5 mg daily dose. The goal was to see if the higher dose led to more hospital visits,…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Kidney patients on higher tamsulosin dose face greater danger?
Knowledge-focused OngoingThis study looked at 14,000 older adults (66+) with advanced chronic kidney disease who started taking tamsulosin. Researchers compared those on a higher dose (0.8 mg/day) to those on a lower dose (0.4 mg/day) to see if the higher dose led to more hospital visits or deaths within…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Newborn kidney health under the microscope: AWAKEN 2.0 launches
Knowledge-focused By invitation onlyThis study looks at how common kidney injury is in newborns in intensive care and what factors increase the risk. Researchers will review medical records of about 4,000 babies from hospitals around the world. The goal is to better understand short- and long-term kidney health, bu…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Heart surgery blood filter shows kidney protection promise in new analysis
Knowledge-focused OngoingThis study re-analyzes data from a previous trial of 343 heart surgery patients who received a blood purification device (oXiris) connected to the heart-lung machine. The original trial found a 12% reduction in acute kidney injury within 7 days. Now researchers will examine how t…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: Hospital Universitari de Bellvitge • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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New lab report design aims to ease anxiety for seniors with kidney disease
Knowledge-focused By invitation onlyThis study tests a new tool that personalizes lab results for older adults (65+) with chronic kidney disease. Researchers want to see if the new reports help patients better understand their results and feel less anxious. About 255 participants will review different report design…
Matched conditions: CHRONIC KIDNEY DISEASE (CKD)
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC