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New antibody drug could unlock kidney transplants for 'impossible' patients

NCT ID NCT05092347

First seen Feb 24, 2026 · Last updated May 20, 2026 · Updated 13 times

Summary

This study tests a drug called vonsetamig in 56 people with chronic kidney disease who are on dialysis and have very high levels of antibodies that make it nearly impossible to find a matching kidney donor. The goal is to safely lower those antibodies so they can receive a kidney transplant. The study will also monitor side effects and how the drug works in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

  • Comprehensive Transplant Center

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Connie Frank Transplant Center at UCSF

    RECRUITING

    San Francisco, California, 94143, United States

  • John Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21224, United States

  • Medstar Georgetown Transplant Institute - 2-PHC

    RECRUITING

    Washington D.C., District of Columbia, 20007, United States

  • New York University Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • Penn Transplant Institute

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of California Irvine

    RECRUITING

    Orange, California, 92868, United States

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • Yale University of Medicine

    RECRUITING

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.