New antibody drug could unlock kidney transplants for 'impossible' patients
NCT ID NCT05092347
First seen Feb 24, 2026 · Last updated May 12, 2026 · Updated 10 times
Summary
This study tests a drug called vonsetamig in people with chronic kidney disease who have very high levels of antibodies that make it nearly impossible to find a matching donor kidney. The goal is to safely lower those antibodies so they can receive a kidney transplant. About 56 adults will take part in this early-phase study to check safety and whether the drug works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Comprehensive Transplant Center
RECRUITINGChicago, Illinois, 60611, United States
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Connie Frank Transplant Center at UCSF
RECRUITINGSan Francisco, California, 94143, United States
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John Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21224, United States
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Medstar Georgetown Transplant Institute - 2-PHC
RECRUITINGWashington D.C., District of Columbia, 20007, United States
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New York University Langone Health
RECRUITINGNew York, New York, 10016, United States
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Penn Transplant Institute
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of California Irvine
RECRUITINGOrange, California, 92868, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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Yale University of Medicine
RECRUITINGNew Haven, Connecticut, 06520, United States
Conditions
Explore the condition pages connected to this study.