CHRONIC KIDNEY DISEASE (CKD)

This study tests whether using specific biomarkers to guide treatment choices can better slow the loss of kidney function in people with chronic kidney disease (CKD) compared to standard care. About 125 adults with CKD and elevated protein in their urine will receive either a tai…

This study tests a program to help doctors better screen and treat chronic kidney disease (CKD) in adults with type 2 diabetes. About 420 participants will receive care through their primary doctor, with the goal of increasing use of recommended medications. The program focuses o…

This study tests whether taking algae supplements (spirulina or seaweed) for 20 weeks can improve heart health markers and gut bacteria in 150 adults aged 50+ with conditions like heart disease, diabetes, or kidney disease. Participants are randomly assigned to receive algae or a…

This study tests a new treatment called AdiaVita, made from umbilical cord stem cells and glutathione, in 100 adults with chronic kidney disease (stages 2-4). Participants receive monthly IV infusions for 3 months and use a skin spray at home. The goal is to see if the treatment …

This study tests whether using diuretics (water pills) as the second blood pressure medication, after standard ACE inhibitors or ARBs, works better than usual care for people with moderate-to-severe chronic kidney disease and uncontrolled high blood pressure. About 720 adults wil…

This study tests a drug called vonsetamig in 56 people with chronic kidney disease who are on dialysis and have very high levels of antibodies that make it nearly impossible to find a matching kidney donor. The goal is to safely lower those antibodies so they can receive a kidney…

This study looks at whether exercise can help older adults (over 55) with chronic kidney disease recover muscle strength and function after being in the hospital. Researchers will compare home-based and supervised exercise programs using muscle measurements and physical tests. Th…

This study tests a program to help Black adults with chronic kidney disease (CKD) reduce their sitting time. Half of the 40 participants will get the program, while the other half receives general CKD education. The goal is to see if reducing sedentary time improves health and qu…

This study tests whether a multimedia video program can help people with early-stage chronic kidney disease improve their physical fitness and daily activity. Sixty adults will be randomly assigned to either watch the videos or receive standard education. Over 12 weeks, researche…

This study follows over 4,000 adults from Shanghai communities to track how heart, kidney, and metabolic diseases develop and change over time. Participants were first checked between 2016-2017 and will be re-assessed through 2035. The goal is to understand risk factors and impro…

This study tests a program to help doctors screen for chronic kidney disease (CKD) in people with type 2 diabetes. Researchers will see if the program increases the number of patients who get the recommended kidney lab tests. The study involves 750 adults who are missing these te…

This study aims to understand why people with cystic fibrosis (CF) often develop kidney disease. Researchers will collect blood and urine samples from 260 participants with CF, both during routine clinic visits and during hospital stays for lung flare-ups. They will look for earl…

This study explores whether a special type of MRI, called manganese-enhanced MRI (MEMRI), can help detect early signs of heart and kidney problems in people with various kidney diseases, including acute kidney injury, chronic kidney disease, and kidney transplant. Researchers wil…

This study aims to make sure lab tests, equipment, and procedures used in research on obesity, diabetes, heart disease, and bone disorders are accurate and give consistent results. It will involve up to 100 healthy volunteers and people with these conditions, aged 18 to 100. The …

This study tests whether a special MRI scan (called MRE) can measure kidney scarring in people with early chronic kidney disease. Currently, doctors use a needle biopsy to check for scarring, which is invasive and can miss patchy damage. The study will follow 200 adults for at le…

This study follows about 20 people with chronic kidney disease who already received the experimental drug vonsetamig and then had a kidney transplant in a previous study. No new treatment is given here. Researchers will track side effects and how well the transplanted kidney work…