ANESTHESIA

This study compares a new method using bioelectrical impedance analysis (BIA) to guide fluid therapy versus standard fluid management in 80 ICU patients after major surgery. The goal is to see if BIA-guided care reduces deaths within 28 days by preventing fluid imbalances. Partic…

This study tests whether a newer sedative drug called remimazolam, combined with a painkiller, is safer than the standard anesthesia for chest surgery. About 50 adults having elective chest surgery will be randomly assigned to receive either the new or standard anesthesia. The ma…

This study tests whether a new combination of sedative and painkiller (anricofen plus ciprofol) can provide safer deep sedation for elderly patients (ages 60–90) undergoing a bile duct procedure called ERCP. The goal is to reduce breathing problems and side effects like nausea, w…

This study compares three drug combinations (propofol with ketamine, dexmedetomidine, or midazolam) for sedation during upper GI endoscopy. Researchers will measure how quickly patients recover and how well the sedation works. The goal is to find the safest and most effective opt…

This study tests whether applying mild electrical stimulation to specific acupoints (Neiguan and Jian Shi) before anesthesia can help prevent dangerous drops in blood pressure during surgery. Researchers will compare two different stimulation frequencies in 84 adults aged 65 and …

This study tests whether a numbing injection (retrolaminar block) given before lumbar spine fusion surgery can lower the amount of opioids needed for pain afterward. About 44 adults will be randomly assigned to receive either the real block or a sham injection. Researchers will t…

This study looks at whether drawing different colors and shapes can help calm adults who are waiting for surgery. About 175 people scheduled for elective surgery will take part. Researchers will measure their anxiety levels before and after the drawing activity to see if it helps…

This study compares a combination of anesthesia methods (multimodal) to standard anesthesia for people having robotic kidney surgery for cancer. The goal is to see if the special approach reduces pain, cuts down on strong painkillers, and allows patients to leave the hospital soo…

This early study tests whether a liquid sedative called dexmedetomidine can safely help children aged 3 to 6 stay still enough for an MRI scan. The goal is to find a dose that works without causing serious side effects, potentially avoiding the need for general anesthesia. Only 1…

This study tests whether gentle electrical stimulation on acupoints can reduce stomach acid backing up into the throat during anesthesia with an i-gel breathing tube. About 116 adults having surgery will be randomly assigned to get the stimulation or not. The goal is to see if th…

This study aims to see which of two common spinal anesthesia drugs helps patients recover faster after outpatient knee replacement surgery. Researchers will compare chloroprocaine and mepivacaine to see which allows patients to move their legs and be discharged from the hospital …

This study looks at whether a common numbing medicine, lidocaine, affects the electrical signals used to monitor nerves during spine surgery. About 44 adults having spine surgery will be randomly assigned to receive either lidocaine or a placebo. The goal is to see if lidocaine c…

This study tests whether showing anesthesiologists a computer-calculated risk score for acute kidney injury (AKI) helps them take steps to prevent it. About 25,500 adults having non-emergency surgery will take part. Doctors will either see the risk score alone, the score plus an …

This study looks at how Danish hospitals prepare patients for anesthesia and what patients care about most before surgery. About 1,000 adults will answer surveys and some will be interviewed. The goal is to improve care by making it more focused on each person's needs and values.

This study looks at how two different types of anesthesia affect inflammation after inguinal hernia repair. Forty adults having elective surgery will be randomly assigned to receive either total intravenous anesthesia (TIVA) or inhaled sevoflurane. Researchers will measure inflam…

This study looks at two different gas flow rates (low vs. minimal) for anesthesia during robot-assisted prostate removal. The goal is to see which one keeps breathing and oxygen levels more stable during surgery. About 70 men having this procedure will take part, and their blood …

This study looks at two ways of giving fluids during liver surgery. One method uses less fluid to try to reduce bleeding, while the other uses more to keep organs working well. The goal is to see which approach leads to fewer serious problems after surgery, like kidney injury. Ab…

This study looks at a new breathing device called SafeLM™, which helps keep a child's airway open during surgery. Researchers will test it in 60 children to see how easy it is to place, how well it seals the airway, and if any problems occur. The goal is to gather information to …

This study looks back at medical records of 300 adults who had a minor amputation (at or below the ankle) to see if the type of anesthesia used affects complications and hospital stay. Researchers will compare general anesthesia, spinal anesthesia, and nerve blocks. The goal is t…

This study will test a computer program that uses artificial intelligence to predict how patients will respond during general anesthesia. The goal is to help doctors monitor patients more proactively, rather than just reacting to changes. About 115 adults having planned surgery w…

This study surveys 200 healthcare professionals (doctors, nurses, and students) to find out which techniques they use when removing breathing tubes from patients after surgery or in intensive care. The goal is to describe current practices, not to test a new treatment. Results wi…

This study looks at whether adding visual aids to the usual written consent form helps patients better understand anesthesia risks and procedures. About 236 adults scheduled for surgery will be randomly assigned to get either standard consent or consent with pictures. Thirty minu…

This study watches brain activity (EEG) in 330 people during routine anesthesia or sedation. It includes children (some with autism), adults over 70, and patients having digestive procedures. The goal is to find patterns that show how deep anesthesia is, without changing any stan…

This study aims to translate and test a questionnaire called QoR-15 for Romanian-speaking adults having planned surgery. The questionnaire measures how well patients recover after anesthesia by asking about pain, comfort, and daily activities. Researchers will enroll 250 people t…

This study looks at how general anesthesia affects certain brain chemicals and thinking skills in adults having gallbladder surgery. Researchers will compare people who have never had anesthesia before with those who have had it multiple times. The goal is to understand if repeat…

This study will test a new breathing device called SaCo VLMA in 20 adults having laparoscopic surgery under general anesthesia. The goal is to see how easy it is to place and how well it helps patients breathe during the procedure compared to other methods. Researchers will measu…

This study tests whether an AI-powered app can improve follow-up for patients who receive continuous regional anesthesia after surgery. About 166 adults will use either the AI app or a standard automated messaging app for three days after their procedure. The goal is to see if th…

This study looks at how to best measure confusion and memory problems that some older people experience after major surgery. Researchers will ask 40 patients aged 70 and older to do memory tests and give blood samples before and after their operation. The goal is to see if these …

This study watches brain activity in 300 adults during high-risk surgeries like heart or spine operations. Researchers use special monitors to track brain waves and pressure, linking them to patient outcomes. The goal is to understand why some people develop confusion or brain in…

This study looks at how two different ways of giving anesthesia gas (low-flow vs normal-flow) affect the heart's electrical signals in 128 adults having gallbladder surgery. The goal is to see if one method is safer for heart rhythm. Participants will have their heart activity mo…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant women before they receive anesthesia during delivery. About 250 first-time mothers will take part. The goal is to see if the quality of the check-up is similar an…

This study will observe 15,000 adults having heart surgery at hospitals worldwide. Researchers will track different anesthesia, heart-lung machine, and surgical methods to see which lead to better recovery and fewer complications. The goal is to gather real-world data to help cre…