Polyp of large intestine

This early-stage trial is testing whether a pill made from freeze-dried healthy donor stool (MTP-101P) is safe and can restore good bacteria in people having part of their colon removed. Forty adults aged 18-75 with colon polyps, early-stage cancer, or diverticulitis will take th…

This study compared two methods for removing non-cancerous colon polyps that are 10-19 mm in size: cold snare (no heat) and hot snare (uses heat). 216 adults undergoing colonoscopy were randomly assigned to one method. The goal was to see if cold snare is as effective and safe as…

This trial tested a new method called underwater ESD for removing large, flat colon polyps. Instead of using gas to inflate the colon, doctors fill it with saline water. The goal was to see if this reduces complications like bleeding or perforation and improves complete removal. …

This study tested whether a device that uses light to monitor blood flow (photoplethysmography) could help doctors manage fluids better during colorectal surgery. The goal was to reduce complications after surgery. 160 adults having colorectal surgery took part. The approach is n…

This study tested a traditional Chinese medicine formula called modified Si Ni San in 32 adults who had colorectal polyps removed. The goal was to see if the herbal treatment could improve gut bacteria balance and reduce inflammation better than standard probiotics. Results may h…

This study compared two procedures for removing large, flat colon polyps (over 25 mm) in 360 adults. One method, ESD, removes the polyp in one piece but has higher risks and costs. The other, EMR, removes it in pieces but is safer and cheaper. The goal was to see which leads to f…

This completed trial tested whether a 3D imaging device helps doctors more accurately classify colon polyps and adenomas during colonoscopy compared to standard 2D imaging. 460 adults with colorectal polyps were randomly assigned to either 3D or 2D imaging before polyp removal. T…

This trial tests how accurately an AI system, called GI Genius, can identify which polyps found during a colonoscopy are adenomas, the type that can become cancer. About 395 adults undergoing screening, diagnostic, or surveillance colonoscopy will receive the AI-assisted procedur…

This trial evaluates an AI-based software tool designed to assist doctors in interpreting colonoscopy images. Using previously collected images and biopsy results from over a thousand patients, the study checks how accurately the AI classifies colorectal lesions as cancerous, pre…

This study tests whether a software called ColoMaia II can help doctors find abnormal growths (polyps) in the colon during a routine colonoscopy. About 600 adults aged 40 to 80 having a screening or diagnostic colonoscopy will be randomly assigned to have the procedure with or wi…

This study tested an artificial intelligence (AI) tool that helps doctors diagnose colorectal polyps during a colonoscopy. The AI analyzes images from a special high-magnification endoscope to predict whether a polyp is cancerous or not. The goal is to improve accuracy and reduce…

This study tested a new laser-based device (AccuMeasure) to measure the size of colon polyps during a colonoscopy. Accurate polyp size is important because it helps doctors decide how often patients need follow-up screenings to prevent colorectal cancer. The study involved 138 ad…

This study tested whether an AI tool (GI Genius) helps doctors find more polyps during colonoscopy in people aged 50-74 who had a previous polyp. Over 1,100 participants were randomly assigned to either AI-assisted or standard colonoscopy. The main goal was to see if AI increases…

This study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45-85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths compar…

This study tested whether a device called Endocuff Vision, which attaches to the tip of a colonoscope and has soft projections to flatten folds in the colon, can help doctors find more sessile serrated adenomas—a type of precancerous polyp. Over 400 adults undergoing routine scre…

This study tested whether an AI tool that highlights suspicious areas during colonoscopy helps doctors find more polyps. Over 400 adults aged 40-80 undergoing screening or diagnostic colonoscopy were randomly assigned to standard colonoscopy or AI-assisted colonoscopy. The main g…

This trial tests whether using a technique called hybrid argon plasma coagulation (h-APC) on the edges of the removal site can prevent colon polyps from growing back after endoscopic mucosal resection (EMR). EMR is a standard procedure for removing large polyps, but when polyps a…

Researchers are reviewing records from 60 people with liver cirrhosis and portal hypertension who had colon polyps removed during a colonoscopy. The goal is to see whether bleeding right after the procedure or in the following days happens more often in this group. The study also…

This study looks at whether a computer-aided diagnosis (CADx) system can help doctors better identify small colorectal polyps (5 mm or smaller) during a colonoscopy. Over 360 doctors will use the system to predict whether polyps are harmless or precancerous. The goal is to see if…

This study looked at 846 people who had a positive stool test for colorectal cancer and needed a follow-up colonoscopy. Researchers wanted to understand how involved patients felt in making decisions about their care and how satisfied they were with the entire screening and treat…

This study tested whether starting a colonoscopy with the patient lying on their back (supine) or on their left side (left-lateral) makes a difference. Researchers measured how long it took to complete the procedure, how much pain patients felt, and how difficult the procedure wa…

This study gathered real-world videos and images from 600 adults undergoing screening or surveillance colonoscopies. The data will be used to develop and test artificial intelligence systems that can help doctors detect colon polyps. The study is complete and focused on data coll…

This study tested a device called Napoleon to help gastroenterology fellows measure colon polyps more accurately during colonoscopies. 46 patients aged 45 and older participated. The goal was to see if using the device improves measurement accuracy compared to just looking, which…

This study tested whether a short training video on 'blink features' (visual clues like redness or ulcers) could help medical students and non-gastroenterology trainees better detect cancer in images of colon polyps. 65 participants completed an online survey before and after wat…

This completed study tested whether an AI system called GI Genius helps doctors spot polyps during colonoscopy. Over 5,000 adults participated. The goal was to see if AI improves detection rates and whether using AI has a lasting learning effect. Results could lead to better colo…

This study looked at the bacteria in the mouth and gut of 126 people with and without serrated polyposis syndrome, a condition that raises the risk of colorectal cancer. Researchers compared the bacteria in people with the syndrome to those with other types of polyps or no polyps…

This study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…

This study tested whether an artificial intelligence system that tracks how long doctors spend examining the colon during a colonoscopy could help them find more polyps. Researchers enrolled 193 adults aged 40 and older undergoing outpatient colonoscopy. The AI calculated effecti…