AI-Guided radiation may shield ovaries in young cancer patients

NCT ID NCT06904365

First seen Jun 24, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests whether a new type of adaptive radiotherapy can reduce radiation exposure to the ovaries in young women (ages 18-50) receiving pelvic radiation for cancers like uterine, rectal, or cervical cancer. Using advanced imaging and an AI treatment planning system, researchers will simulate treatments on 10 patients to see if they can keep ovarian radiation doses low without compromising cancer treatment. This is a computer-based feasibility trial, not a treatment study, so it aims to gather knowledge for future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HyperSight CBCT scan and ETHOS 2.0 AI treatment planning system

What this could lead to

If successful, this could show that adaptive radiotherapy is a feasible way to protect ovarian function in young women needing pelvic radiation.

What could go wrong

This is a very small, early feasibility study using computer simulations, not actual patient treatment. It may not translate to real-world benefits or work for all cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal carcinoma anus neoplasm breast cancer breast neoplasm cervical carcinoma colon carcinoma colonic neoplasm gastric cancer gastric neoplasm head and neck cancer Head and Neck Neoplasms liver cancer Liver Neoplasms lung cancer lung neoplasm rectal cancer rectal neoplasm sarcoma urinary bladder carcinoma Urinary Bladder Neoplasms uterine cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States