New pill plus immunotherapy shows promise for Hard-to-Treat cancers
NCT ID NCT06362369
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 18 times
Summary
This study tests an experimental oral drug called 7HP349 (Alintegimod) combined with standard immunotherapy drugs (ipilimumab and nivolumab) in adults with advanced solid tumors like melanoma, lung, kidney, or liver cancer that have not responded to prior treatments. The goal is to find safe doses and see if the combination works better than standard therapy. About 126 participants will take part in two phases: first to check safety, then to compare effectiveness.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brown University Health Cancer Institute
RECRUITINGProvidence, Rhode Island, 02906, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dartmouth Hitchcock
RECRUITINGLebanon, New Hampshire, 03756, United States
Contact
Contact Phone: •••-•••-••••
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Florida Cancer Specialists
COMPLETEDLake Mary, Florida, 32746, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
Contact Phone: •••-•••-••••
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University of Colorado Cancer Center
RECRUITINGAurora, Colorado, 84005, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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