Endoscopic obesity treatments under 10-Year microscope

NCT ID NCT05725967

ENROLLING_BY_INVITATION Disease control Sponsor: Christopher C. Thompson, MD, MSc Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will follow 5,000 adults who have had endoscopic procedures for weight loss, such as stomach stapling through a scope or gastric balloons. Researchers will track weight, blood pressure, diabetes, and cholesterol for up to 10 years to see how well these procedures work long-term. The goal is to better understand which treatments help people keep weight off and improve related health conditions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Endoscopic procedures (e.g., sleeve gastroplasty, intragastric balloons, aspiration therapy)
What this could lead to: If successful, this could show which endoscopic procedures work best for long-term weight loss and reducing obesity-related health problems like diabetes and high blood pressure.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may take up to 10 years and depend on participants staying in the study.

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Conditions

The condition(s) this trial relates to.

Abdominal Pain Anastomotic Leak Gastric Fistula gastric ulcer iatrogenic disease morbid obesity Obesity obesity disorder Obesity, Abdominal Postoperative Complications Weight Gain Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ABDOMINAL OBESITY ABDOMINAL PAIN BARIATRIC SURGERY CANDIDATE COMPLICATION OF SURGICAL PROCEDURE COMPLICATION OF TREATMENT COMPLICATION POSTOPERATIVE DELAYED GASTRIC EMPTYING FOLLOWING PROCEDURE FISTULA, GASTRIC LEAK, ANASTOMOTIC OBESITY OBESITY ASSOCIATED DISORDER OBESITY, MORBID ROUX-EN-Y ANASTOMOSIS SITE ULCER, GASTRIC WEIGHT GAIN WEIGHT LOSS

Endoscopic obesity treatments under 10-Year microscope

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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