Pioneering trial tests cancer drug on patients with 'Double Trouble' autoimmune conditions

NCT ID NCT03816345

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is testing the safety and effects of the immunotherapy drug nivolumab in people who have both advanced cancer and an autoimmune disease like lupus, rheumatoid arthritis, or Crohn's disease. It will enroll 300 adults to see if the drug can help control their cancer while also monitoring how it affects their autoimmune condition. The main goal is to understand the risks and find the right dose for this unique patient group.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

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Emory University Hospital/Winship Cancer Institute
ACTIVE_NOT_RECRUITING

Atlanta, Georgia, 30322, United States
HaysMed
RECRUITING

Hays, Kansas, 67601, United States

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Contact Phone: •••-•••-••••
Huntsman Cancer Institute/University of Utah
ACTIVE_NOT_RECRUITING

Salt Lake City, Utah, 84112, United States
Johns Hopkins University/Sidney Kimmel Cancer Center
RECRUITING

Baltimore, Maryland, 21287, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Laura and Isaac Perlmutter Cancer Center at NYU Langone
RECRUITING

New York, New York, 10016, United States

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Lawrence Memorial Hospital
RECRUITING

Lawrence, Kansas, 66044, United States

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M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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Massachusetts General Hospital Cancer Center
RECRUITING

Boston, Massachusetts, 02114, United States

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MedStar Georgetown University Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States

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Mercy Hospital Pittsburg
SUSPENDED

Pittsburg, Kansas, 66762, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
RECRUITING

New York, New York, 10032, United States

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NYP/Weill Cornell Medical Center
RECRUITING

New York, New York, 10065, United States

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NYU Langone Hospital - Long Island
RECRUITING

Mineola, New York, 11501, United States

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National Cancer Institute Developmental Therapeutics Clinic
RECRUITING

Bethesda, Maryland, 20892, United States

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National Institutes of Health Clinical Center
ACTIVE_NOT_RECRUITING

Bethesda, Maryland, 20892, United States
Northwestern University
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60611, United States
Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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Salina Regional Health Center
RECRUITING

Salina, Kansas, 67401, United States

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Siteman Cancer Center at Christian Hospital
RECRUITING

St Louis, Missouri, 63136, United States

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Siteman Cancer Center at Saint Peters Hospital
RECRUITING

City of Saint Peters, Missouri, 63376, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Siteman Cancer Center at West County Hospital
RECRUITING

Creve Coeur, Missouri, 63141, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Siteman Cancer Center-South County
RECRUITING

St Louis, Missouri, 63129, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Smilow Cancer Center/Yale-New Haven Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

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Stanford Cancer Institute Palo Alto
ACTIVE_NOT_RECRUITING

Palo Alto, California, 94304, United States
The University of Kansas Cancer Center - Olathe
RECRUITING

Olathe, Kansas, 66061, United States

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Thomas Jefferson University Hospital
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UT Southwestern Clinical Center at Richardson/Plano
RECRUITING

Richardson, Texas, 75080, United States

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UT Southwestern Simmons Cancer Center - RedBird
RECRUITING

Dallas, Texas, 75237, United States

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UT Southwestern/Simmons Cancer Center-Dallas
RECRUITING

Dallas, Texas, 75390, United States

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UT Southwestern/Simmons Cancer Center-Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States

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University Health Network-Princess Margaret Hospital
SUSPENDED

Toronto, Ontario, M5G 2M9, Canada
University Health Truman Medical Center
RECRUITING

Kansas City, Missouri, 64108, United States

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University of Alabama at Birmingham Cancer Center
ACTIVE_NOT_RECRUITING

Birmingham, Alabama, 35233, United States
University of California Davis Comprehensive Cancer Center
RECRUITING

Sacramento, California, 95817, United States

Contact Phone: •••-•••-••••

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University of Chicago Comprehensive Cancer Center
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60637, United States
University of Kansas Cancer Center
RECRUITING

Kansas City, Kansas, 66160, United States

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University of Kansas Cancer Center - Lee's Summit
RECRUITING

Lee's Summit, Missouri, 64064, United States

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University of Kansas Cancer Center - North
RECRUITING

Kansas City, Missouri, 64154, United States

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University of Kansas Cancer Center at North Kansas City Hospital
RECRUITING

North Kansas City, Missouri, 64116, United States

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University of Kansas Cancer Center-Overland Park
RECRUITING

Overland Park, Kansas, 66210, United States

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University of Kansas Clinical Research Center
RECRUITING

Fairway, Kansas, 66205, United States

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University of Kansas Health System Saint Francis Campus
RECRUITING

Topeka, Kansas, 66606, United States

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University of Kansas Hospital-Indian Creek Campus
RECRUITING

Overland Park, Kansas, 66211, United States

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University of Kansas Hospital-Westwood Cancer Center
RECRUITING

Westwood, Kansas, 66205, United States

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University of Kentucky/Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States

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University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Wayne State University/Karmanos Cancer Institute
ACTIVE_NOT_RECRUITING

Detroit, Michigan, 48201, United States
Yale University
RECRUITING

New Haven, Connecticut, 06520, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

AUTOIMMUNE DISEASE CROHN DISEASE DERMATOMYOSITIS HEMATOPOIETIC AND LYMPHOID CELL NEOPLASM INFLAMMATORY BOWEL DISEASE MALIGNANT SOLID NEOPLASM MULTIPLE SCLEROSIS PSORIASIS PSORIATIC ARTHRITIS RHEUMATOID ARTHRITIS SJOGREN SYNDROME SYSTEMIC LUPUS ERYTHEMATOSUS SYSTEMIC SCLERODERMA ULCERATIVE COLITIS