New pill targets Hard-to-Treat cancers with AKT1 mutation

NCT ID NCT07038369

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 28 times

Summary

This early-stage study tests an experimental pill, ATV-1601, in adults with advanced solid tumors or certain breast cancers that have a specific AKT1 gene change. The main goals are to find a safe dose and check how the drug moves through the body. About 134 participants will take the drug alone or with another medicine (fulvestrant) to see if it can help control their cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Leon Berard

    Lyon, 69008, France

  • Florida Cancer Specialists & Research Institute - Lake Mary

    Lake Mary, Florida, 32746, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • National Cancer Centre Singapore

    Singapore, 168583, Singapore

  • START Madrid - CIOCC

    Madrid, 28050, Spain

  • USC Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.