Virginia Commonwealth University
Clinical trials sponsored by Virginia Commonwealth University, explained in plain language.
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Can a Pre-Transplant weight loss program improve kidney transplant success?
Disease control CompletedThis study tests a program that helps people with obesity who are waiting for a kidney transplant lose weight. Participants will receive education, a calorie tracking app, a continuous glucose monitor, a weight scale, and a food scale. The goal is to see if this program is practi…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Ultrasound and guidance help pregnant women with addiction get care
Disease control CompletedThis study tested a program that combines community-based fetal ultrasound with care navigation to help pregnant women with substance use disorder engage in prenatal care and substance use treatment. The program used motivational interviewing and strength-based education to suppo…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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New headset therapy may reduce need for repeat eye surgeries in kids
Disease control CompletedThis study tests a non-surgical treatment for intermittent exotropia, a condition where one eye drifts outward. Children aged 4-7 will use a special headset for one hour daily, six days a week, for 12 weeks. The goal is to improve eye control and reduce the need for surgery.
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Neighborhood chats help shed pounds in petersburg
Disease control CompletedThis study tested a weight loss program for African American adults in Petersburg, VA, using informal house chats instead of a clinic setting. The goal was to see if this approach could help people eat better, move more, and lose weight. Twenty-two participants took part, and the…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Could a depression drug help fight opioid addiction?
Disease control CompletedThis early-phase study tested whether adding a medication called Auvelity (a combination of dextromethorphan and bupropion) to standard buprenorphine treatment is safe and might help reduce cravings, withdrawal, and negative feelings in people with opioid use disorder. 18 adults …
Phase: PHASE1, PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Can virtual health coaches help kids lose weight?
Disease control CompletedThis study tested a new way to help children with obesity by replacing some in-person doctor visits with virtual house calls. Ten children aged 9-13 and their parents worked with a health coach through video calls and exercise sessions over 24 weeks. The goal was to see if famili…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Parent coaching may help teens keep weight off
Disease control CompletedThis completed study tested two ways parents can help teens with obesity maintain weight loss. 418 teens (ages 12-16) and their parents took part. One group focused on teaching parents coaching skills, the other on helping parents lose weight themselves. Both groups included teen…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Urine test may outsmart blood test for kidney rejection
Diagnosis CompletedThis study tests whether a urine test for a protein called CXCL10 can catch kidney transplant rejection that a standard blood test misses. Researchers will compare the urine test to biopsy results in 50 kidney transplant patients. They will also check if the urine samples can be …
Sponsor: Virginia Commonwealth University • Aim: Diagnosis
Last updated Jul 17, 2026 00:00 UTC
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Rural teens eat more veggies after school program
Prevention CompletedThis study tested a school-based program to help rural seventh graders eat more fruits and vegetables. Over 1,100 students from ten Virginia middle schools took part. The program included goal setting, peer leaders, and classroom workshops. Results showed that students in the pro…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Prevention
Last updated Jun 26, 2026 18:47 UTC
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Can a buddy app slash hospital readmissions for liver patients?
Prevention CompletedThis study tested a smartphone app called PatientBuddy designed to help people with cirrhosis and their caregivers manage care at home. The goal was to reduce avoidable hospital readmissions within 30 days after discharge. Researchers enrolled 232 patients and their caregivers to…
Sponsor: Virginia Commonwealth University • Aim: Prevention
Last updated Jun 26, 2026 15:11 UTC
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App aims to ease perinatal depression in thousands of women
Symptom relief CompletedThis study tested a mobile app called Mamma Mia, designed to support mental health during pregnancy and after childbirth. Nearly 2,000 pregnant women used the app, which offers mindfulness exercises, breastfeeding tips, and relationship advice. Researchers measured changes in dep…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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VR therapy shows promise for teens with conduct disorder
Symptom relief CompletedThis study tested a virtual reality program called Impact VR to help youth aged 10-17 with conduct disorder learn to recognize and regulate emotions. The program involved four weekly sessions in a private setting. Researchers measured changes in callous-unemotional traits, conduc…
Phase: PHASE1 • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Virtual reality boosts arm recovery in stroke patients
Symptom relief CompletedThis study tested whether using an immersive virtual reality (VR) headset along with practice of everyday arm tasks could improve arm movement in people who had a stroke at least 6 months earlier. 13 adults with limited arm motion took part. Their arm movement was measured before…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Vibrating vest may help Parkinson's patients stop freezing
Symptom relief CompletedThis study tested a wearable device called PDVibe2 that delivers vibration therapy to improve walking and balance in people with Parkinson's disease. 12 participants with mild to moderate Parkinson's used the device while researchers measured their gait and movement. The goal was…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Weighted blankets tested to calm ICU delirium
Symptom relief CompletedThis study tested whether weighted blankets can help prevent or reduce delirium in adult ICU patients. 49 participants used the blankets, and researchers measured satisfaction from patients, their families, and healthcare providers. The goal was to see if this simple, non-drug ap…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Brain tumor patients get help for 'Chemo Brain' with new telehealth program
Symptom relief CompletedThis pilot study tested a telehealth program called C-SMART for people with primary brain tumors who have mild memory or thinking problems. The program combines cognitive rehabilitation with mindfulness training over 8 weekly sessions. Researchers enrolled 32 patients and caregiv…
Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Could virtual reality calm anxious kids at the doctor?
Symptom relief CompletedThis study examined whether virtual reality (VR) can help lower anxiety in children aged 6-15 during medical procedures. Researchers analyzed data from 168 pediatric patients who used VR as part of a quality improvement program. They measured changes in heart rate, blood pressure…
Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can a home exercise program help men on prostate cancer hormone therapy?
Symptom relief CompletedThis study tested a remote exercise program for 27 men with prostate cancer who were receiving hormone therapy (androgen deprivation therapy). The program included walking or cycling, strength training, and counseling sessions over 8 weeks. The main goal was to see if the program…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Talking therapy shows promise for brain cancer distress
Symptom relief CompletedThis study tested a therapy called Managing Cancer and Living Meaningfully (CALM) to see if it helps people with brain cancer feel less distressed. 60 adults with brain tumors or brain metastases who had high depression or death anxiety took part. The study measured how many peop…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Brain tumor insomnia targeted by CBT in new pilot study
Symptom relief CompletedThis study tested a type of talk therapy called Cognitive Behavioral Therapy for Insomnia (CBT-I) in 70 people with brain tumors who also had trouble sleeping. The therapy involved six weekly group sessions delivered online. The main goal was to see if the approach was practical …
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Sleep coaching shows promise for heart failure patients in tiny pilot
Symptom relief CompletedThis pilot study tested whether sleep coaching and sleep hygiene training could help people with a common type of heart failure (HFpEF) sleep better and feel better. Ten participants wore activity trackers and kept sleep diaries to see if they could gradually extend their sleep t…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 26, 2026 14:03 UTC
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Can exercise MRI reveal hidden heart issues in pacemaker patients?
Knowledge-focused CompletedThis study looks at whether it is safe and possible to do a special exercise test (MRI combined with a bike workout) in 20 people who already have a specific type of pacemaker. The goal is to see how different pacemaker settings affect the heart's pumping ability during light exe…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Could a digital stethoscope keep sick babies out of the ER?
Knowledge-focused CompletedThis study looks at whether a new digital stethoscope can help parents of infants with fast heart rates (tachyarrhythmia) record clear heart readings at home. About 100 babies under 1 year old will take part. The goal is to see if parents can capture good-quality ECGs, which migh…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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Tiny plastic bumps could make your invisalign work better
Knowledge-focused CompletedThis study tested three different sizes of clear aligner attachments (small bumps on the teeth) to see which one helps move the upper lateral incisors outward most predictably. Twenty-eight people with mild crowding or spacing were treated with Invisalign. The goal was to find th…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Teachers' Long-Term use of classroom program under microscope
Knowledge-focused CompletedThis study followed 52 teachers and 72 students to see how well teachers continued using the BEST in CLASS program a year after training. Researchers measured how closely teachers stuck to the program and how students' behavior changed. The goal was to understand what helps or hi…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Racial divide in smoking and stress: new study seeks answers
Knowledge-focused CompletedThis completed study examined how African American and white male smokers respond to stress and how that affects their smoking habits. Researchers used a psychological stress test and measured daily cortisol patterns to understand biological differences. The goal is to learn why …
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Study reveals impact of E-Cig flavor bans on black smokers
Knowledge-focused CompletedThis study involved 71 African American menthol smokers to see how the availability of e-cigarette flavors like menthol or tobacco changes their smoking habits, toxin exposure, and addiction risk. Participants were surveyed daily about cigarette use and tested for carbon monoxide…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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E-Cig flavor showdown: do menthol and tobacco hook smokers differently?
Knowledge-focused CompletedThis study looked at how different e-cigarette flavors and nicotine levels influence addiction potential in 32 adult smokers. Participants tried tobacco-flavored e-cigs with varying nicotine strength, menthol e-cigs, and their own cigarettes, then reported how much they'd be will…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New study maps key tests for LGMD to speed up drug development
Knowledge-focused CompletedThis study involved 116 people with Limb Girdle Muscular Dystrophy (LGMD), a group of rare muscle-weakening disorders. Researchers measured how well participants could walk, move their arms, and breathe, and asked about their daily activities and overall health. The goal was to i…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Richmond study shines light on black Girls' strengths, not just struggles
Knowledge-focused CompletedThis completed study looked at the quality of life of Black girls in Richmond, Virginia, focusing on their strengths and community resources rather than problems. Researchers surveyed 339 Black adolescent girls aged 12-17 and interviewed parents and young adults. The goal was to …
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Sweetness and nicotine form in vapes may change how people puff
Knowledge-focused CompletedThis study tested how different e-cigarette liquids—varying in sweetness and nicotine form—affect blood nicotine levels, puffing behavior, and how people feel. Thirteen healthy adults who use cigarettes, e-cigarettes, or both took part. Researchers measured nicotine in the blood,…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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E-Cig study reveals nicotine delivery differences
Knowledge-focused CompletedThis study looked at how different e-liquid nicotine strengths in e-cigarettes affect nicotine levels in the blood and smoking behavior. 33 healthy adult smokers took part. The goal was to understand how e-cigarette settings influence nicotine delivery and use.
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Liver transplant study probes gut Compound's link to heart risk
Knowledge-focused CompletedThis study looked at how a gut-related compound called TMAO affects heart health in 19 adults who had a liver transplant. Researchers measured TMAO levels and checked blood vessel function to understand why heart disease is more common after transplant. The goal was to gather kno…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Vaping alcohol: can E-Cigs fool breathalyzers?
Knowledge-focused CompletedThis study tested whether using e-cigarettes that contain ethanol (alcohol) can change the results of breath, blood, or oral fluid alcohol tests, as well as field sobriety tests. Twelve adults who use e-cigarettes and drink alcohol took part. The goal was to understand if vaping …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Small study probes genetic roots of Alcohol-Fueled aggression
Knowledge-focused CompletedThis study looked at how a person's genes might change the way they think and act after drinking alcohol. Nine healthy adults completed tasks measuring aggression after consuming alcohol or a placebo. The goal was to better understand why some people react differently to alcohol,…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Rideshare training helps autistic adults get around on their own
Knowledge-focused CompletedThis study tested a training program to help autistic adults learn to use rideshare services like Uber or Lyft. 13 autistic adults took part to see if the training was acceptable and helpful. The goal was to give them more freedom to travel independently for work, social events, …
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Water heroes: can a school program get kids to hydrate?
Knowledge-focused CompletedThis pilot study tested a school-based program to encourage kids to drink more water. The program included student ambassadors, a kick-off event, and a student-led marketing campaign. Researchers looked at whether the program was feasible and if it could improve hydration, reduce…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Neighbor-Led weight loss program shows promise in underserved communities
Knowledge-focused CompletedThis study tested whether training local community members as wellness coaches could help African American adults in economically disadvantaged areas manage their weight. Researchers recruited and trained coaches to lead a 12-week group lifestyle program. The goal was to see if t…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Can a smartphone app keep cirrhosis patients out of the hospital?
Knowledge-focused CompletedThis study tested whether a health app (Patient Buddy and EncephalApp) plus scheduled follow-up calls and visits could reduce avoidable hospital readmissions within 30 days in 232 cirrhosis patients. Patients and their caregivers were trained on the app and received daily contact…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:34 UTC
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Blanket battle: does placement matter for C-Section warmth?
Knowledge-focused CompletedThis study looked at 124 women having planned C-sections to see if placing a forced-air warming blanket on the upper body or under the body keeps core temperature more stable. Both blanket positions are already used in hospitals. The goal was to find the best spot to prevent heat…
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:36 UTC