E-Cig flavor showdown: do menthol and tobacco hook smokers differently?

NCT ID NCT05971823

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different e-cigarette flavors and nicotine levels influence addiction potential in 32 adult smokers. Participants tried tobacco-flavored e-cigs with varying nicotine strength, menthol e-cigs, and their own cigarettes, then reported how much they'd be willing to pay and use each product. The goal is to understand which product features make smoking more or less addictive, helping guide future regulations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
electronic cigarette with varying flavors and nicotine levels
What this could lead to
If successful, this could help regulators understand which e-cigarette flavors and nicotine strengths are less addictive, potentially guiding policies to reduce smoking harm.
What could go wrong
This is a small, completed lab study with only 32 participants, so results may not apply to real-world use or larger populations. It measures hypothetical choices, not actual long-term behavior.

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Conditions

The condition(s) this trial relates to.

Tobacco Use Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for the Study of Tobacco Products

    Richmond, Virginia, 23220, United States

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