Can changing your vape flavor lower inflammation?
NCT ID NCT05423340
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether switching from banned e-cigarette flavors (like fruit or candy) to a tobacco flavor or using nicotine pouches could reduce signs of inflammation in daily vapers. 163 participants were randomly assigned to one of these options. The goal was to see if these changes could lower health risks associated with vaping.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
E-cigarette flavor (tobacco) and tobacco-free nicotine pouches
What this could lead to
If switching to less toxic flavors reduces inflammation, it could point toward safer ways to use nicotine products.
What could go wrong
This is a small, completed trial with no long-term follow-up. The results may not apply to all vapers, and switching flavors may not lower health risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Roswell Park Comprehensive Cancer Center
Buffalo, New York, 14206, United States