Can changing your vape flavor lower inflammation?

NCT ID NCT05423340

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether switching from banned e-cigarette flavors (like fruit or candy) to a tobacco flavor or using nicotine pouches could reduce signs of inflammation in daily vapers. 163 participants were randomly assigned to one of these options. The goal was to see if these changes could lower health risks associated with vaping.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
E-cigarette flavor (tobacco) and tobacco-free nicotine pouches
What this could lead to
If switching to less toxic flavors reduces inflammation, it could point toward safer ways to use nicotine products.
What could go wrong
This is a small, completed trial with no long-term follow-up. The results may not apply to all vapers, and switching flavors may not lower health risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14206, United States

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