Virginia Commonwealth University

This study tests whether a newer drug, letermovir, works better than the standard valganciclovir to prevent CMV (a common virus) in African American kidney transplant recipients. About 30 high-risk patients will take letermovir for 6 months after transplant, and their results wil…

This study gives 30 adults with conditions like diabetes, high blood pressure, or obesity free fruits and vegetables for 12 months. Researchers want to see if this "produce prescription" improves food security, diet quality, and health measures like blood sugar. Participants must…

This study tests a transition program for teens and young adults (ages 16-22) with type 1 diabetes as they move from pediatric to adult care. About 109 participants and their caregivers will use the program to improve blood sugar control, diabetes self-care, and clinic attendance…

This early-stage study tests two drugs, niraparib and neratinib, together in people with advanced solid tumors or ovarian cancer that no longer responds to platinum chemotherapy. The goal is to find the safest dose and see if the combination can stop the cancer from growing for a…

This study tested a shorter course of radiation (hypofractionation) to the breast and nearby lymph nodes in 137 women with node-positive breast cancer. The goal was to see if this approach reduces long-term side effects like arm swelling (lymphedema) while still controlling cance…

This study tests whether giving two immunotherapy drugs (decitabine and pembrolizumab) before standard chemotherapy can increase immune cell activity in breast tumors. It involves 46 people with locally advanced HER2-negative breast cancer, divided by hormone receptor status. The…

This study tests whether a drug called anakinra, which reduces inflammation, can help prevent heart failure in people who have had a heart attack. About 84 adults who recently had a severe heart attack will receive the drug. The goal is to see if blocking the body's inflammatory …

This study looks at whether taking vitamin D supplements can lessen nerve pain caused by taxane chemotherapy. About 120 people with low vitamin D levels who are starting chemo will be randomly assigned to get vitamin D or standard care. The goal is to see if vitamin D helps reduc…

This study tests whether a small vibrating device worn on the wrist can improve hand movement and feeling in people who had a stroke at least six months ago. The device uses gentle vibrations to boost touch sensation, which may help with grip and dexterity. The main goal is to se…

This study tests whether using remote monitoring devices and video doctor visits helps people with chronic conditions like diabetes and high blood pressure feel more confident managing their health. About 40 adults will use a tablet or phone to send health data to their care team…

This study looks at how often antiepileptic drugs and other psychoactive medications are prescribed in US nursing homes, especially before and after the COVID-19 pandemic. Researchers will analyze data from millions of long-stay residents to see if these drugs are being used more…

This study reviews medical records from 8,000 people who had weight-loss surgery at one hospital. Researchers want to learn how different surgeries affect weight loss, safety, and health problems like diabetes. The goal is to use this information to help future patients get bette…

This study looks at whether a community-wide approach called Healthy Communities for Youth can reduce violence among young people. It includes a hospital-based program for injured youth and activities that promote positive development. About 3,390 teens aged 12-17 and their paren…