University Of Zurich

This study tested if doing special breathing exercises before abdominal surgery could lower the number and severity of complications after the operation. 134 adults scheduled for major belly surgery were randomly assigned to do these exercises or not. The goal was to see if pre-s…

This study tested whether the drug acetazolamide can reduce the rise in lung blood pressure that happens when healthy adults travel to high altitude (3600 meters). 303 men and women took either the drug or a placebo. The goal was to see if the drug's effect differs between sexes.…

This study tested a procedure called left atrial appendage occlusion (LAAO) against standard blood-thinning medications in 81 people with atrial fibrillation who were also getting a new heart valve (TAVI). The goal was to see if LAAO could prevent strokes and bleeding better than…

This study looked at whether giving extra oxygen to people who live above 2500 meters and have high blood pressure in their lungs (high altitude pulmonary hypertension) can reduce that pressure. 48 adults took part, and researchers measured changes in lung blood pressure with oxy…

This study looked at whether a special type of MRI (multiparametric MRI) can more accurately determine how far bladder cancer has spread. Knowing the exact stage helps doctors decide the best treatment, such as surgery alone or chemotherapy before surgery. The study included 186 …

This study tested whether a simple home exercise program and/or protein supplements could help prevent falls in older adults at risk of muscle loss (sarcopenia). Over 800 seniors who were already frail or had low protein intake took part. The goal was to see if these easy, low-co…

This study looked at whether the drug acetazolamide, used to prevent acute mountain sickness (AMS), works the same in women and men. Over 300 healthy adults were randomly given either the drug or a placebo before going to high altitude. The goal was to see if women, who may have …

This study tested a new approach for chronic tinnitus: combining mild electrical brain stimulation (tRNS) with white noise. 35 adults with persistent tinnitus received either the real treatment or a sham (fake) version. The goal was to see if this combo could temporarily reduce t…

This study tested Pycnogenol, a natural pine bark extract, against a placebo in 153 adults with Long COVID. The goal was to see if it improves overall health and reduces symptoms like fatigue and brain fog. Participants took the supplement for 12 weeks and reported their health s…

This study tested whether a higher, more focused dose of radiation (SBRT) works better than standard radiation for relieving pain from spinal tumors that have spread from other cancers. 219 adults with confirmed cancer and painful spinal metastases took part. The main goal was to…

This study tested whether a drug called acetazolamide can improve sleep-disordered breathing in women traveling to high altitude (3600 m). 303 healthy adults participated in a randomized, placebo-controlled trial. The main goal was to see if the drug reduced drops in oxygen level…

This study looked at whether giving extra oxygen to people who live high in the mountains and have a type of high blood pressure in their lungs helps them walk farther. Twenty-four adults who live above 8,200 feet took part. Researchers measured how far they could walk in 6 minut…

This study looked at whether people with pulmonary vascular disease (a condition affecting blood vessels in the lungs) can exercise just as well without extra oxygen. Forty adults walked for 6 minutes, once with nasal oxygen and once breathing regular air. The goal was to see if …

This study tested a short, low-intensity psychological program called Problem Management Plus (PM+) for refugees and asylum seekers experiencing stress and trauma. The program was delivered by non-professionals in local communities. The goal was to see if the program was feasible…

This study looked at how a specially designed shoe sole, called the X10D, affects walking in healthy adults aged 50 to 65. The goal was to see if the sole makes walking more active and dynamic compared to regular shoes. Fifteen participants walked on a treadmill with pressure pla…

This study looked at how high altitude (3600 meters) affects sleep-disordered breathing in women depending on their menstrual cycle phase. 91 healthy, non-smoking women aged 18-44 participated. Researchers measured oxygen levels and breathing patterns during sleep to see if the m…

This study looked at 70 people with normal pressure hydrocephalus (NPH), a condition that causes walking problems, memory loss, and bladder control issues. The goal was to find better ways to predict which patients would benefit from a surgery that places a shunt (a tube) to drai…

This study looked at how men and women's brains and hearts react to mental stress. Researchers used special brain scans to measure activity in stress-related areas and blood flow to the heart in 64 healthy adults aged 50-75. The goal was to understand if sex-related factors and p…

This study looked at the DNA of 9 people with primary immune deficiency whose genetic cause was unknown. Researchers used advanced gene sequencing to find new mutations that might cause the condition. The goal was to better understand the disease, not to test a treatment.

This study looked at 24 people with high altitude pulmonary hypertension who live above 8,200 feet. Researchers measured how far they could walk in 6 minutes at their home altitude (10,500 feet) and after moving to a lower altitude (2,500 feet). The goal was to see if relocating …

This study checked if people allergic to house dust mites and seafood are also sensitive to edible insects. 96 adults completed skin prick and blood tests. The goal was to see if insect sensitization is more common in this group compared to those with dust mite allergy alone. Res…

This study looked at whether chemicals in saliva can show when a driver is dangerously sleepy. Over 500 drivers in Belgium gave a saliva sample and reported how tired they felt. Researchers hope to find a biological test that could help prevent accidents caused by drowsy driving.

This study looked at how a robotic body-weight support system called 'the FLOAT' changes the way people move during daily tasks like walking, standing up, and climbing stairs. About 65 people with incomplete spinal cord injury and healthy volunteers took part in a single session.…

This study tested whether walking training on real ground with body weight support helps people with chronic spinal cord injury walk better than treadmill training. Fourteen adults with incomplete spinal cord injury participated in 4 weeks of either overground or treadmill traini…

This study tested whether drugs that boost serotonin (like some psychedelics) increase pro-social behavior compared to drugs that boost dopamine. 122 healthy adults completed tasks measuring empathy, generosity, and social bonding. The goal was to understand how brain chemicals i…

This study tested whether a special type of MRI (multiparametric MRI) can reliably measure kidney function in people with metabolic syndrome—a cluster of conditions like obesity, high blood pressure, and high blood sugar. Researchers compared MRI results between 46 healthy volunt…

This study looked at how lung volume changes when stable preterm babies are placed in car seats. Using a special imaging technique, researchers measured breathing in 51 infants born before 37 weeks. The goal was to understand if the semi-upright car seat position affects lung aer…

This study looked at whether giving breathing support through a nose tube during intubation helps newborns stay stable. 50 babies who needed a breathing tube were included. The goal was to see if this method improves first-attempt success and reduces drops in oxygen or heart rate…

This study looked at how people with different neurological conditions (like stroke, Parkinson's, or spinal cord injury) walk compared to healthy individuals. Researchers measured walking patterns to create "gait profiles" for each condition. The goal was to better understand how…

This study looked at a new way to measure pain and stress in premature babies who need a breathing treatment called LISA. The researchers tested a skin conductance device alongside a standard pain scale in 21 infants. The goal was to see if this method could help doctors decide w…

This completed study looked at nearly 500 adults with irritable bowel syndrome (IBS) to see how common FODMAP intolerance and joint hypermobility are. Researchers tested participants with breath tests and physical exams, and explored how these factors relate to gut bacteria and b…

This study looked at 24 people with high-altitude pulmonary hypertension who live above 2,500 meters. Researchers measured their sleep breathing at a high altitude (3,200 m) and again after moving to a low altitude (760 m). The goal was to see if relocating to lower ground improv…

This study looked at 366 people who had a type of bleeding stroke called aneurysmal subarachnoid hemorrhage. Researchers measured hemoglobin levels in their spinal fluid to see if it could predict secondary brain injury, such as delayed brain damage or artery narrowing. The goal …

This study tested whether personalized walking training based on detailed 3D movement analysis works better than standard walking therapy. 63 people with spinal cord damage from injury or multiple sclerosis took part. The goal was to see if customizing exercises to each person's …

This study followed 91 healthy women traveling to 3600 meters altitude to see if their menstrual cycle phase influenced their risk of acute mountain sickness (AMS). Researchers tracked symptoms like headache and nausea using standard questionnaires. The goal was to understand whe…

This study tested whether digital intraoral scans are as accurate as traditional dental impressions for capturing full-arch teeth. Ten healthy adults received both conventional impressions and multiple digital scans. Researchers compared the scans to see how precise and true the …

This study looked at whether people with chronic lung disease who experience low oxygen during exercise can walk just as far without extra oxygen as with it. Forty adults with stable lung disease completed a 6-minute walk test both on room air and on low-flow nasal oxygen. The go…

This study looked at whether the BCG vaccine, normally used to prevent tuberculosis, could reduce the amount of hidden HIV in the body (the latent reservoir) in people already on HIV medication. Sixty adults with well-controlled HIV took part. The main goal was to measure changes…

This study looked at 24 people with high altitude pulmonary hypertension (HAPH) who live above 2,500 meters. Researchers measured their lung blood pressure at 3,200 meters and then after moving to 760 meters for one night and seven nights. The goal was to see if simply being at a…