University Of Zurich

This study tests a weekly, image-guided radiation therapy for men with very high-risk prostate cancer that has not spread widely. Fifty-four participants will receive five precise radiation sessions over five weeks, with the radiation plan adjusted each week based on CT or MRI sc…

This study tests a new approach called pharmacoscopy, which uses a lab test on a patient's tumor sample to find the most effective drugs for their specific cancer. It involves 40 adults with brain tumors like glioblastoma that have not responded to standard treatments. The goal i…

This phase II trial tests whether vortioxetine, a drug currently used for depression, can help people with newly diagnosed glioblastoma. The study will enroll 78 adults and measure if the drug extends the time before the cancer worsens. Vortioxetine was selected because lab tests…

This study tests whether a new MRI contrast agent, gadopiclenol, can detect brain metastases earlier than standard methods in 180 patients with advanced lung, breast, or skin cancer. Early detection may offer more treatment options and prevent neurological symptoms. Participants …

This study looks at whether a special MRI scanner (low-field) can help doctors deliver precise radiation therapy for prostate cancer in people who have both hips replaced. Standard MRI often produces blurry images near metal implants, making treatment planning difficult. The rese…

This study tests whether a new flexible cable (SuperCable) helps the breastbone heal faster and with less pain than the standard steel wire after heart surgery. About 86 adults will be randomly assigned to one of the two closure methods. Researchers will check healing with CT sca…

This study looks at how well the body handles phosphate from food as people age and whether men and women respond differently. Researchers will give a phosphate drink to 40 healthy volunteers aged 18-25 and 63-70, then measure phosphate levels in the blood. The goal is to underst…

This study looks at a new way to assess pain in intensive care patients who are on breathing machines and cannot speak. It uses a special tool (AlgiScan) and a behavioral checklist to adjust pain medicine more safely. Researchers will compare data from 400 adults to see if the ne…

This study aims to better understand heart failure by looking at the molecules in patients' blood and tissues. Researchers will study 500 adults with heart failure to find patterns that could predict how the disease will progress. The goal is to discover new targets for future tr…

This study will ask 1800 young people and people with low incomes in Lucerne and Zurich how satisfied they are with free HIV and STI testing and counseling. The goal is to see if these free services work well and are easy to access. Participants just fill out a questionnaire afte…

This small study looks at whether transferring healthy donor stool into the gut can change the bacteria of people with type 2 diabetes and stable coronary artery disease. Thirty adults will get the transplant via colonoscopy and be monitored for six months. The main goal is to se…

This study looks at how different ways of processing soy (like heating or fermenting) change its ability to cause allergic reactions. Researchers will test processed soy in the lab and then on the skin of 55 adults with soy allergy. The goal is to understand which processing meth…