University Of Virginia
Clinical trials sponsored by University Of Virginia, explained in plain language.
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Smart tech aims to tame type 1 diabetes by learning your personality
Disease control CompletedThis study tested if a smart continuous glucose monitor (CGM) system could better manage type 1 diabetes than standard sensor-augmented therapy. Researchers wanted to see if customizing the system's advice based on a person's psychological and behavioral traits could improve bloo…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 01, 2026 23:41 UTC
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Trial tests new way to stop bleeding in tiny hearts
Disease control CompletedThis study compared two different treatments to help control serious bleeding in babies under 2 years old after heart surgery. Researchers tested a purified protein powder (fibrinogen concentrate) against a standard blood product (cryoprecipitate) to see which one was better at h…
Phase: PHASE4 • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Smart app aims to take the guesswork out of diabetes insulin doses
Disease control CompletedThis small study tested if a smartphone app could simplify mealtime insulin dosing for adults with type 1 diabetes. Instead of counting carbs, participants used the app to estimate meals. The goal was to see if this simpler method could help control blood sugar levels as well as …
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Digital tool aims to curb sugary drink habit in High-Risk region
Disease control CompletedThis study tested whether a web and text-message program called iSIPsmarter could help adults in rural Appalachia cut back on sugary drinks like soda and sweet tea. Researchers compared it to a basic educational website. The goal was to see if the interactive program was better a…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New program aims to help cancer survivors live healthier lives
Disease control CompletedThis study tested a lifestyle program designed to help women who have finished treatment for endometrial cancer. The program used online lessons and weekly group meetings to encourage healthier eating, more exercise, and better mental well-being. Researchers wanted to see if this…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Could a tiny sensor replace finger pricks for diabetes management?
Disease control CompletedThis small, completed study tested if a new method for adjusting daily insulin doses works better than the standard method. It compared using data from a continuous glucose monitor (CGM) sensor to using traditional fingerstick checks. The goal was to see if the CGM method helped …
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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One pill, two addictions? study tests drug for drinking and smoking
Disease control CompletedThis study tested whether a medication called topiramate could help people who struggle with both alcohol dependence and smoking. Over 200 participants received either the medication or a placebo, along with counseling, and were followed to see if they could reduce heavy drinking…
Phase: PHASE2, PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Robot pump could find your perfect insulin dose in just 10 days
Disease control CompletedThis small pilot study tested if using an automated insulin pump for just 10 days could safely and quickly help find the right daily insulin dose for adults with type 2 diabetes. Researchers compared blood sugar control in 23 participants who either used the pump or followed stan…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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Robot pancreas put to the test in teens
Disease control CompletedThis study aimed to see if an automated insulin delivery system (an 'artificial pancreas') helps teenagers with type 1 diabetes better manage their blood sugar levels over two years, especially during puberty. It involved 42 adolescents, comparing those using the automated system…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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Your phone could soon test your balance
Diagnosis CompletedThis study tested whether a new smartphone app could accurately measure gaze stability and balance function in adults with inner ear disorders. Researchers compared the app's measurements to those from a standard, expensive clinic machine. The goal is to create a low-cost, access…
Sponsor: University of Virginia • Aim: Diagnosis
Last updated Mar 30, 2026 14:35 UTC
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Can a phone app ease the emotional burden for breast cancer survivors?
Symptom relief CompletedThis study tested whether a publicly available mobile app (IntelliCare) could help reduce depression and anxiety in breast cancer survivors. It involved 313 women diagnosed within the past five years who reported elevated symptoms. The research also explored if adding human coach…
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Brain scan may predict which Parkinson's patients walk better on common drug
Symptom relief CompletedThis small study explored whether a drug called donepezil (Aricept) could help improve walking and balance in people with Parkinson's disease. Researchers tested five participants to see if the drug's effect was linked to the size of a specific brain area involved in movement. Th…
Phase: PHASE2 • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Could a common stomach issue be secretly scarring your lungs?
Knowledge-focused CompletedThis study aimed to understand if a hiatal hernia, where part of the stomach pushes into the chest, might cause very early lung injury before any lung disease is diagnosed. Researchers compared 14 adults with a hiatal hernia to those without, looking for signs of stomach fluid in…
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Scientists film skin to unlock secrets of muscle pain
Knowledge-focused CompletedThis small study aimed to understand how stiff muscle tissue feels by filming skin movement during massage. Researchers applied washable ink to participants' backs and used cameras to record how the skin stretched when a physical therapist performed assessments and massage. The g…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists use helium scans to map how air moves in diseased lungs
Knowledge-focused CompletedThis study aimed to measure how air flows through the lungs of healthy people and those with COPD (chronic obstructive pulmonary disease). Researchers used a special MRI scan with inhaled helium gas to create detailed airflow maps. The data helps validate computer models that pre…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Computer sleuths hunt for clues to stop deadly infections in preemies
Knowledge-focused CompletedThis was a pilot study to see if it's possible to build a computer warning system for two serious conditions in very small premature babies: sepsis (a bloodstream infection) and necrotizing enterocolitis (a severe intestinal disease). Researchers reviewed past medical records fro…
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Scientists test if harder workouts curb appetite
Knowledge-focused CompletedThis study aimed to understand how different workout intensities affect a hormone called ghrelin, which controls hunger and metabolism. Researchers compared high and low-intensity exercise in 40 lean and obese adults, some with prediabetes, to see how it changed hormone levels, a…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:42 UTC