University Of Virginia

This study tests whether adding steroids and stronger antibiotics to standard care improves survival for HIV patients with severe sepsis in Africa. Researchers will compare different treatment combinations in 344 hospitalized adults to see which approach works best. The goal is t…

This study aims to find the most effective antibiotic treatment for a condition where too much bacteria grows in the small intestine (SIBO) in children from Bangladesh. Researchers believe treating SIBO could help prevent stunted growth and malnutrition. The trial will test diffe…

This study aims to find the most effective way to give weekly feedback to people in a weight loss program. About 127 adults with obesity or overweight will track their diet, activity, and weight, and receive weekly messages from a coach. Researchers will test if the tone and cont…

This study aims to find the best ear to operate on for people with hearing loss who also have a weak balance system in one inner ear. Researchers will test if putting the cochlear implant in the ear with worse balance function leads to less dizziness after surgery compared to ope…

This study aims to see if combining regular exercise with a weight loss medication (tirzepatide) works better for weight loss and improving health than taking the medication alone. It will involve 24 adults aged 30-65 who have overweight or obesity. Participants will take the med…

This early-stage study is testing a new personalized therapy for people with advanced breast or prostate cancer that has spread and stopped responding to standard treatments. Doctors collect a patient's own immune cells, modify them in a lab to better target cancer, and then infu…

This study is testing a new portable device designed to measure how loose or 'wobbly' an ankle joint is. Researchers want to see if the device gives accurate and consistent readings in healthy people, those who have recovered from a sprain, and those with ongoing ankle instabilit…

This study aims to develop a better MRI scan to measure the type of fat around the heart. Researchers will use this new scan in people with a common form of heart failure to see if the fat's makeup is linked to their condition. They will also test if this scan can predict who mig…