University Of Virginia
Clinical trials sponsored by University Of Virginia, explained in plain language.
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Scientists supercharge immune cells to fight advanced breast cancer
Disease control OngoingThis early-phase trial is testing a two-part treatment for women whose breast cancer has spread. Doctors take a patient's own immune cells, modify them in a lab to better target cancer, and then infuse them back alongside a drug called pembrolizumab. The main goals are to find a …
Phase: PHASE1, PHASE2 • Sponsor: University of Virginia • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Could a diabetes drug fix damaged blood vessels?
Disease control TerminatedThis study is testing if a medication called dulaglutide can improve the health of tiny blood vessels in the muscles of adults with type 1 diabetes. Researchers believe better blood flow might help the body use insulin more effectively. The trial is currently suspended and was co…
Phase: PHASE2 • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Study seeks better PCOS care for women nearing menopause
Disease control TerminatedThis study aimed to find out if women with PCOS in their 40s were just as satisfied taking metformin as they were taking birth control pills. It planned to have women try each medication for six months and measure their quality of life, symptoms, and health markers. The goal was …
Phase: EARLY_PHASE1 • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Pharmacists on the front lines: new program aims to help smokers quit, even if They're not ready
Disease control OngoingThis study is testing a new program where pharmacists at community health centers help low-income smokers quit or cut back on cigarettes. It aims to help 100 smokers, including those who aren't yet ready to quit completely. The program provides support and nicotine replacement th…
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Could a common drug stop Alzheimer's before it starts?
Prevention OngoingThis study is testing whether the drug memantine can help prevent Alzheimer's disease in people who are at high risk but don't yet have symptoms. It involves 32 adults aged 50-65 who have a family history of Alzheimer's and carry a specific genetic risk factor. The main goal is t…
Phase: PHASE2 • Sponsor: University of Virginia • Aim: Prevention
Last updated Apr 01, 2026 21:56 UTC
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Can extra classroom lessons stop school violence before it starts?
Prevention OngoingThis study tested whether adding special social skills lessons called R-CITY to a standard school curriculum could help prevent violence and improve classroom behavior. The program taught students skills like recognizing emotions, responding appropriately, building relationships,…
Phase: NA • Sponsor: University of Virginia • Aim: Prevention
Last updated Mar 23, 2026 15:16 UTC
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New school program aims to stop teens from smoking and vaping
Prevention OngoingThis study is testing a program called UP2UTobacco, designed to help 9th-grade students quit or avoid using tobacco and e-cigarettes. Researchers first talked with students to design the program, then are testing it in schools by comparing it to no program at all. The goal is to …
Phase: NA • Sponsor: University of Virginia • Aim: Prevention
Last updated Mar 20, 2026 14:48 UTC
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Smartphones and fitbits track cancer drug side effects in real-time
Knowledge-focused OngoingThis study is testing a remote monitoring system to better track symptoms and side effects in lung cancer patients taking oral targeted therapy pills. Participants use a smartphone app, a Fitbit watch, and a smart pill bottle cap for up to 24 weeks. The goal is to see if this sys…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:56 UTC
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Scientists track hidden insulin changes during pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to learn how the body's response to insulin changes before, during, and after pregnancy in people with Type 1 Diabetes. Researchers will analyze existing data from 100 participants who used specific glucose monitors and insulin pumps during a past pregnancy. The g…
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC