PCOS treatment showdown: metformin vs. birth control for older women

NCT ID NCT03905941

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study aimed to see if metformin or birth control pills were more satisfying for treating PCOS in women aged 40-49. It planned to use a quality-of-life questionnaire to measure patient satisfaction. However, the study was withdrawn before any participants were enrolled, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Metformin and oral combined hormonal contraceptives (ethinyl estradiol/norethindrone acetate)
What this could lead to
If it had succeeded, this could have helped guide treatment choices for PCOS in older women based on patient satisfaction.
What could go wrong
The study was withdrawn before enrolling any participants, so no results are available. It was also very early-phase and small in scope.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22901, United States

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