Could a common drug stop Alzheimer's before it starts?

NCT ID NCT05063851

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether memantine, a drug already used for Alzheimer's symptoms, might help prevent the disease in people at high risk. Researchers are testing it in 32 adults aged 50 to 65 who have a family history of dementia and carry the ApoE4 gene. The main goal is to see if this approach is practical for a larger prevention trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

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