University Of Oklahoma

This study tests whether adding the immunotherapy drug pembrolizumab to standard radiation and chemotherapy can help control high-risk endometrial cancer after surgery. About 45 participants who have had a hysterectomy will receive radiation to the vagina, followed by three cycle…

This study tests a drug called TPST-1495 in 10 people with endometrial or colorectal cancer who are scheduled for surgery. The drug targets specific receptors to help the immune system fight cancer. Researchers will check blood and tumor samples before and after treatment to see …

This early-stage study tested whether adding an experimental drug called OKN-007 to standard chemotherapy and radiation is safe for people with newly diagnosed glioblastoma, an aggressive brain cancer. About 27 adults who had surgery for their tumor took part. The main goal was t…

This study looks at whether a simple, 30-second ECG test using a handheld device can find hidden atrial fibrillation (an irregular heartbeat) in cancer patients aged 65 and older. About 494 participants will be randomly assigned to either get the quick screening or usual care. Th…

This study tests a new imaging tool called MSOT that uses light and sound to create detailed pictures of neck lymph nodes in people with head and neck cancer. The goal is to see if it can more accurately find cancer that has spread to lymph nodes and also detect tissue damage fro…

This study compares two biopsy methods—MRI fusion and micro-ultrasound—to see which better detects aggressive prostate cancer. It involves 29 men with suspected cancer or on active surveillance. The goal is to find a more accessible screening option for underserved communities.…

This early study looks at whether taking low-dose aspirin for two weeks before surgery can change the cells and immune environment in the fallopian tubes. Researchers want to see if these changes might lower the risk of developing fallopian tube cancer. The study involves 18 wome…

This study tests whether giving early breathing support (CPAP) to late preterm babies (34-37 weeks) born by C-section can reduce the need for intensive care. About 120 newborns will be randomly assigned to receive CPAP right after birth or standard care. The goal is to see if thi…

This study was designed to test a new smoking cessation program for adults who identify as sexual or gender minorities and experience high social stress. The program adds volunteer community activities to standard quit-smoking support. The study was withdrawn before enrolling any…

This study examines a protein called DCAMKL-1, which may be a stem cell marker in pancreatic cancer. Researchers will measure its levels in 60 patients before and after standard treatment to see how it changes. The goal is to learn more about the disease, not to test a new treatm…

This study was designed to see if a mobile health app helps patients with recurrent head and neck or gynecologic cancers track their symptoms and quality of life. Researchers planned to ask patients about their experience using the app and whether they found it easy and useful. T…

This study works with the Choctaw Nation to find better ways to get people screened for lung cancer. Researchers will talk to patients and doctors to understand barriers, then test a program that helps eligible people get screened and quit smoking. The goal is to catch lung cance…