University Of Oklahoma

This study is testing whether combining two drugs, niraparib (a daily pill) and dostarlimab (an IV infusion every few weeks), can help control recurrent or progressive cervical cancer. It aims to see if the combination is safe and if it shrinks tumors or stops them from growing. …

This early-stage study is testing whether combining two drugs—avelumab and AVB-S6-500—is safe for people with advanced bladder cancer that has spread or can't be surgically removed. The trial involves 19 participants who have already tried standard platinum-based chemotherapy. Re…

This study is testing if a smartphone app that gives financial rewards can help low-income adults quit smoking for good. The app uses a breath sensor and facial recognition to remotely verify that a person has not smoked, then automatically sends them money. Researchers are compa…

This study is testing a new treatment plan for people with a high risk of their endometrial (uterine) cancer coming back after surgery. It combines a short course of targeted radiation with an immunotherapy drug (pembrolizumab) and then adds chemotherapy. The main goal is to see …

This study is testing whether a combination of two immunotherapy drugs can help control advanced endometrial cancer that has returned or spread. The trial will involve 110 women whose cancer has progressed despite previous chemotherapy. Researchers will measure whether tumors shr…

This is an early-stage study to see if adding an experimental drug called OKN-007 to the standard treatment (temozolomide and radiation) is safe and tolerable for people newly diagnosed with an aggressive brain cancer called glioblastoma. The main goal is to find the highest dose…

This study is testing a new imaging device called MSOT that uses light and sound to create pictures. It aims to see if it can better identify affected lymph nodes in head and neck cancer patients and monitor scarring from radiation treatment. The study will involve 100 patients a…

This study is testing a new experimental imaging device called MSOT. It uses light and sound waves to take pictures of inflammation through the skin in people with Crohn's disease, colitis, or graft-versus-host disease. The main goal is to check if the device is safe and if its i…

This study is testing whether a new, high-resolution micro-ultrasound technology can find serious prostate cancer as well as or better than the current standard MRI-guided biopsy. It involves about 30 men who are either suspected of having prostate cancer or are already being mon…

This study is testing a new smartphone app designed to help African American men learn about prostate cancer and complete PSA screening tests at home. Researchers will compare the new app to an existing government health app to see if it's more effective at increasing knowledge a…

This study is testing whether giving a gentle, steady flow of air (called CPAP) to late preterm babies immediately after they are born by C-section can help them breathe better on their own. The goal is to see if this early support can prevent breathing difficulties and reduce th…

This small, early-stage study is exploring whether taking low-dose aspirin for two weeks before surgery can reduce inflammation in the fallopian tubes. It involves 18 women who are already scheduled to have their fallopian tubes removed for non-cancer reasons. The main goal is to…

This study aimed to test a smartphone app for patients with recurrent head, neck, or gynecologic cancers. The goal was to see if the app was easy to use and helpful for patients to report their daily symptoms, quality of life, and any barriers to their care during treatment. The …

This small, early-stage study is testing a new oral drug called TPST-1495 in patients with endometrial or colorectal cancer who are already scheduled for surgery. The goal is to see if taking the pill for one week before surgery changes the immune system's activity in the blood a…

This study looks back at medical records to understand how well immunotherapy cancer drugs work for American Indian patients compared to White patients. Researchers will analyze survival times, side effects, and cancer-related deaths in 72 patients who were treated between 2015 a…

This study aimed to test whether a special electromagnetic device could influence the nervous system in people with heart failure. Researchers planned to measure heart rate changes in 40 participants (20 with heart failure, 20 healthy) while they received either real or fake trea…