New combo therapy for endometrial cancer shows promise in early trial

NCT ID NCT03932409

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial is testing whether adding the immunotherapy drug pembrolizumab to standard radiation and chemotherapy is safe and feasible for people with high-intermediate risk endometrial cancer. About 45 participants who have already had surgery to remove the uterus will receive radiation to the vagina, followed by three cycles of pembrolizumab plus chemotherapy. The main goal is to see how many people can complete all three cycles of the combined treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • LSU Health New Orleans

    New Orleans, Louisiana, 70112, United States

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States