Aspirin may alter fallopian tubes, early study hints at cancer prevention

NCT ID NCT03771651

Ongoing Knowledge-focused Sponsor: University of Oklahoma Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests whether taking a low dose of aspirin daily for two weeks before surgery can change the immune environment of the fallopian tubes. Researchers will compare tissue from 18 women who take aspirin to control samples, looking for signs of reduced inflammation and lower cancer-related changes. The goal is to understand if aspirin could one day help prevent fallopian tube cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aspirin 81 mg
What this could lead to: If successful, this could point toward a simple, low-cost way to reduce fallopian tube inflammation and potentially lower cancer risk.
What could go wrong: This is a very early, small pilot study with only 18 participants. It looks at biological changes, not actual cancer prevention, so results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fallopian tube cancer fallopian tube neoplasm salpingitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FALLOPIAN TUBE CANCER FALLOPIAN TUBE INFECTION

Contacts and locations

Locations

Stephenson Cancer Center, University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73117, United States

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