Promising drug cocktail targets Hard-to-Treat ovarian cancer

NCT ID NCT06494150

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a combination of nab-sirolimus (Fyarro) and fulvestrant (Faslodex) in 37 people with recurrent low-grade serous ovarian cancer. The goal is to see if the drugs can shrink tumors or stop them from growing. Participants receive the drugs intravenously and by injection over 21-day cycles, and researchers will track response rates and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nab-sirolimus (Fyarro) and fulvestrant (Faslodex)

What this could lead to

If successful, this combination could offer a new treatment option for people with recurrent low-grade serous ovarian cancer, potentially slowing or shrinking tumors.

What could go wrong

This is a small, early-phase study with only 37 participants, so results may not apply to everyone. Side effects from the drugs could be serious, and the treatment may not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ovarian cancer ovarian serous adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OU Health Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73117, United States