Can a Sugar-Like supplement boost fertility in PCOS?
NCT ID NCT04407754
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a myo-inositol supplement to the standard fertility drug letrozole helps women with polycystic ovary syndrome (PCOS) achieve pregnancy. About 168 women will receive either the supplement or a placebo alongside letrozole for up to 5 treatment cycles. The goal is to see if the combination leads to more clinical pregnancies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
myo-inositol and D-chiro inositol supplement
What this could lead to
If it works, this could offer a simple, low-cost supplement to boost pregnancy chances for women with PCOS taking letrozole.
What could go wrong
This is a small pilot trial, so results may not be definitive. The supplement might not improve pregnancy rates over letrozole alone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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OUHSC Reproductive Medicine Clinic
Oklahoma City, Oklahoma, 73104, United States