Could a vitamin B3 pill protect the brain's blood vessels in Parkinson's?
NCT ID NCT07703137
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This trial investigates whether nicotinamide riboside (NR), a form of vitamin B3, can improve blood vessel health in the brain, memory, and physical function in people with Parkinson's disease. Participants are randomly assigned to take either NR or a placebo daily for 12 weeks. Researchers measure changes in brain blood flow, cognitive test scores, and physical performance to see if NR offers any benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nicotinamide riboside (a form of vitamin B3)
- What this could lead to
- If it works, this could point toward a simple dietary supplement that helps preserve brain blood vessel function and slow cognitive or physical decline in Parkinson's disease.
- What could go wrong
- This is a small, early-stage trial with only 40 participants, so results may not apply broadly. The supplement may show no benefit over placebo, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON'S DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Center for Geroscience and Healthy Brain Aging
Oklahoma City, Oklahoma, 73117, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Wild blueberries put to the test for Parkinson's motor symptoms
- Could tailored brain stimulation quiet Parkinson's tremors more effectively?
- Zapping away tremors: scientists probe how electrical stimulation calms shaky hands
- Could a sleep disorder hold the key to Parkinson's pain?
- Zapping the brain without surgery: a new hope for Parkinson's?
- Which balance test best predicts falls in Parkinson's? a head-to-head comparison