New drug duo aims to tackle returning cervical cancer
NCT ID NCT04068753
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial is testing whether combining two drugs, niraparib and dostarlimab, can help shrink or control cervical cancer that has come back or spread. About 66 women with recurrent or progressive cervical cancer will receive the treatment. The goal is to see how many respond and how safe the combination is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
niraparib and dostarlimab
What this could lead to
If successful, this combination could offer a new treatment option to help control recurrent or progressive cervical cancer.
What could go wrong
This is a Phase 2 trial with only 66 participants, so results are preliminary. The combination may not work for everyone and could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Louisiana State University Health Science Center
New Orleans, Louisiana, 70112, United States
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Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, 46202, United States
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Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22903, United States