University Of Oklahoma

This study tested a special drilling technique called osseodensification, which compresses bone instead of removing it, to prepare the jaw for dental implants. Twenty-three adults with missing teeth received about 40 implants using this method. The goal was to see if the techniqu…

This study tested whether offering small gift cards for quitting smoking helps low-income smokers stay smoke-free. 320 uninsured or Medicaid patients received either standard care (counseling and medication) or standard care plus financial rewards for verified abstinence. The mai…

This pilot study tested whether giving late preterm babies (34-37 weeks) born by C-section a short course of CPAP breathing support right after delivery could reduce their need for extra oxygen or breathing help. 120 babies were randomly assigned to receive either early CPAP or s…

This study looked at how sitagliptin (Januvia) affects levels of anti-rejection drugs and blood sugar in 16 people who had a kidney transplant and have type 2 diabetes. Participants took sitagliptin daily for 3 months. The goal was to see if it is safe and works well in this grou…

This study looked at whether giving nicotine products to caregivers who smoke and don't want to quit can reduce the smoke their children breathe. 74 caregivers and their kids took part. The main goal was to measure changes in kids' exposure to smoke using a saliva test.

This pilot study tested whether delivering the drug paclitaxel directly to the leg artery during angioplasty could reduce the chance of the artery narrowing again. 27 adults with leg pain from blocked arteries took part. The main goal was to see if the drug helped keep the artery…

This pilot study tested whether taking a daily supplement called nicotinamide riboside (a form of vitamin B3) for 4 weeks could improve blood vessel function and thinking skills in 8 older adults with peripheral artery disease. Researchers measured changes in blood flow in the ar…

This study tested whether giving nicotine lozenges, e-cigarettes, or dissolvable tobacco lozenges to caregivers who smoke could reduce the amount of secondhand smoke their children are exposed to. The 89 participating caregivers were not interested in quitting smoking but were wi…

This study tested two ways to help women with cervical dysplasia stop smoking: nicotine patches, gum, or lozenges versus electronic cigarettes. Thirty-one women participated for six weeks. The goal was to see if these methods are acceptable and help reduce or stop smoking. It was…

This early-phase trial tested whether putting heparin directly into the bladder can reduce the number of urinary tract infections (UTIs) in women who get them often. 34 women with recurrent UTIs received either heparin or a placebo (saline) bladder wash. The study measured how ma…

This study tested whether an iPhone ECG device (AliveCor) can accurately measure the QT interval of the heart compared to a standard 12-lead ECG. Researchers studied 29 hospitalized patients starting medications that can affect the QT interval. The goal was to see if the iPhone r…

This study tested a brief therapy called CBT-NC in 57 children aged 6-17 who have frequent nightmares and suicidal thoughts. The goal was to see if the therapy could reduce nightmare distress and improve overall mental health. Children were either given the therapy right away or …

This study tested a pelvic support girdle called FemmeJock in 100 women with pelvic organ prolapse. Participants wore the girdle during daytime physical activity for 3 months. The goal was to see if it improved symptoms like pelvic pressure and bulging, and whether women were sat…

This study tested if a gentle electrical stimulation on the ear (transcutaneous vagal stimulation) could improve blood vessel function in 11 people with peripheral artery disease (PAD). The goal was to see if this non-invasive method could help blood vessels relax and work better…

This study tested a gentle electrical stimulation of a nerve in the ear (called tVNS) to see if it could reduce inflammation and improve heart function and exercise ability in people with a type of heart failure called HFpEF. 52 adults with HFpEF received either the real stimulat…

This study tested a mobile app called STAMP+CBT for advanced cancer patients with chronic pain. The app helps patients track their pain, mood, and opioid use while providing tailored education and cognitive behavioral therapy (CBT) exercises. Fifty-two patients used the app for 4…

This study tested a smartphone app called OKquit to help smokers quit. About 500 adults who wanted to stop smoking were split into two groups: one got standard helpline support plus daily check-ins, and the other got that plus the OKquit app. The goal was to see if the app helped…

This study looked at how not having enough healthy food (food insecurity) can lead to insulin resistance in people living with HIV. Researchers tested a community-based "food as medicine" program that provided healthy food and taught cooking and self-care skills. The goal was to …

This study looked at whether a nutrition training program for family child care home providers could improve the food they serve to young children. 72 providers in Oklahoma took part, with half getting the nutrition program and half a comparison on environmental health. Researche…

This study tested whether doing leg strength exercises while restricting blood flow (using a cuff) builds more muscle and strength than regular training. Eight healthy adults completed different types of leg workouts. The goal was to see if blood flow restriction could make low-l…

This study looked at how doing a mental task while exercising affects muscle fatigue in healthy adults aged 18-35 and 65-90. Researchers measured changes in arm strength, anxiety, blood pressure, and fatigue using questionnaires and a custom device. The goal was to understand the…

This study looked at whether the depth of anesthesia during surgery affects a person's ability to hear spoken words without being aware of it, and whether this influences anxiety after surgery. Seventy adults having urologic or orthopedic procedures took part. The goal was to und…

This completed Phase 1 study tested whether taking L-Citrulline, a dietary supplement, for one week can improve blood vessel function in the brain and eyes of healthy young and older adults. Researchers measured brain activity and blood flow using special imaging techniques. With…

This study tested whether time-restricted eating (eating only during certain hours of the day) could improve blood vessel health and brain function in older adults at risk for age-related memory decline. Researchers measured changes in brain blood flow and electrical activity in …

This study tested a smartphone app that sends daily parenting tips to parents of young children in home visiting programs. The goal was to see if the app could help parents engage in more positive interactions with their kids, building resilience. Twenty-four parents completed th…