University Of Oklahoma

This study tested whether delivering the drug paclitaxel directly to the leg artery during a standard balloon procedure can help keep the artery from narrowing again. 27 adults with blocked leg arteries (peripheral artery disease) took part. The goal was to see if this approach i…

This early-phase study tested whether rinsing the bladder with heparin, a blood thinner, could lower the number of urinary tract infections (UTIs) in women who get them often. 34 women with a history of repeat UTIs took part. The goal was to see if heparin could help prevent bact…

This study tested a gentle electrical stimulation of a nerve in the ear (called tVNS) in 52 older adults with a type of heart failure where the heart pumps normally but is stiff. The goal was to see if daily one-hour sessions for three months could reduce inflammation and improve…

This small pilot study tested whether taking a daily NAD supplement for 4 weeks could improve blood vessel function, brain blood flow, and thinking skills in 8 older adults with peripheral artery disease (PAD). Researchers measured changes in artery health, cognitive tests, and b…

This study tested a brief therapy called CBT-NC in 57 children aged 6-17 who have chronic nightmares. The goal was to see if the therapy could reduce nightmare distress and frequency, and improve overall mental health and suicidal thoughts. Children were randomly assigned to rece…

This study tested a special girdle called FemmeJock, worn outside underwear, to see if it helps women with pelvic organ prolapse feel better. 100 women with stage 2 or higher prolapse used the girdle for 3 months. The goal was to see if they were satisfied, kept using it, and if …

This study tested whether a smartphone app that sends daily parenting tips can help parents interact more positively with their young children. Twenty-four parents in home visiting programs used the app for four weeks, reporting their emotions and parenting activities. The goal w…

This study looked at whether doing leg exercises with a blood flow restriction cuff (like a tight band) can help build muscle strength and size better than regular weight training. Eight healthy adults took part, and researchers measured their leg muscle force and body compositio…

This study tested whether a supplement called L-Citrulline can improve blood vessel function in the brain and body of healthy young and older adults. Twenty participants took the supplement and had their brain activity and blood flow measured using special scans. The goal was to …

This study looked at how doing a mental task at the same time as a physical exercise affects tiredness in healthy adults aged 18-35 and 65-90. Researchers measured changes in arm strength, anxiety, blood pressure, and fatigue using questionnaires and a special device. The goal wa…

This study checked if an iPhone ECG recording can measure the heart's QT interval as accurately as a standard 12-lead ECG. Researchers studied 29 hospitalized patients starting medications that can affect the QT interval. The goal was to see if the iPhone could be a reliable tool…

This study tested whether time-restricted eating (eating only during certain hours) could improve blood vessel and brain function in adults aged 55 to 80. Researchers measured changes in brain blood flow and cognitive performance. The goal was to see if this eating pattern might …

This study looked at whether the level of anesthesia affects a person's ability to hear spoken words without being aware of it, and whether this affects anxiety after surgery. Researchers studied 70 adults having urologic or orthopedic surgery. The goal was to understand how deep…