University Of Missouri-columbia
Clinical trials sponsored by University Of Missouri-columbia, explained in plain language.
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Heart stiffness drug shows promise in Insulin-Resistant adults
Disease control CompletedThis study tested whether amiloride, a drug that blocks a salt channel in blood vessels, can improve artery stiffness in overweight adults with insulin resistance. 137 men and women (pre- and post-menopausal) participated. The goal was to see if the drug could help control a key …
Phase: PHASE2, PHASE3 • Sponsor: University of Missouri-Columbia • Aim: Disease control
Last updated Apr 26, 2026 20:02 UTC
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Brain training after stroke shows big gains in everyday tasks
Symptom relief CompletedThis study tested a special thinking strategy training (called CO-OP) to help people who had a stroke improve their ability to do everyday activities like dressing or cooking. 72 adults who had a stroke within the last 9 months took part. The training focused on using problem-sol…
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Apr 29, 2026 04:28 UTC
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Can a single pill before surgery cut opioid use after kidney stone treatment?
Symptom relief CompletedThis study looked at whether giving a single dose of pregabalin before kidney stone surgery could lower pain and reduce the need for opioid painkillers afterward. About 118 adults having ureteroscopy with a ureteral stent were randomly given either pregabalin or a placebo. The ma…
Phase: PHASE2, PHASE3 • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Apr 26, 2026 20:01 UTC
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Can a phone app turn bystanders into overdose heroes?
Knowledge-focused CompletedThis study tested a new system called the Opioid Rapid Response System (ORRS) that uses a smartphone app to alert and train everyday people to respond to opioid overdoses with the life-saving drug naloxone. Over 700 adults from communities using the PulsePoint app took part. The …
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC