University Of Missouri-columbia

This study tested whether amiloride, a drug that blocks a salt channel in blood vessels, can improve artery stiffness in overweight adults with insulin resistance. 137 pre- and postmenopausal women and age-matched men participated. The goal was to see if the drug could reduce the…

This study tested whether a dietary supplement called phosphatidylserine (PS) can improve blood flow in people with type 2 diabetes. The supplement blocks an enzyme (ADAM17) that may interfere with insulin's ability to widen blood vessels. 36 adults with type 2 diabetes took part…

This study tested a new system called the Opioid Rapid Response System (ORRS) that uses a smartphone app to train and alert everyday people to respond to opioid overdoses with the life-saving drug naloxone. Over 700 adults from communities using the PulsePoint app took part. The …

This study looked at whether treating insomnia with cognitive behavioral therapy (CBT) can also reduce pain in women with fibromyalgia. 131 women participated, receiving sleep therapy and tracking their sleep, pain, and stress levels. The goal was to see if improving sleep could …

This study looked at whether treating chronic insomnia with a 4-week behavioral program can improve thinking and memory in adults over 65. 62 older adults with insomnia completed sleep diaries and daily thinking tests before, right after, and 3 months after treatment. The goal wa…

This study tested whether a cognitive strategy training program, delivered remotely, is practical and helpful for people with long COVID who experience memory and thinking problems. 65 adults with post-COVID cognitive symptoms participated. The program aimed to improve their abil…

This study tested whether giving a single dose of pregabalin about an hour before kidney stone surgery (ureteroscopy with stent placement) could reduce pain and the need for opioid painkillers afterward. 118 adults participated, receiving either pregabalin or a placebo. The main …

This study tested a thinking-based therapy called metacognitive strategy training (MCST) in 72 people who had a stroke within the past 9 months. The therapy focuses on teaching problem-solving skills to improve daily activities like dressing or cooking, rather than just repetitiv…

This study tested two different drugs used to reverse the effects of a muscle relaxant (rocuronium) after elective spine surgery. The goal was to see if one drug (sugammadex) causes less urinary retention (trouble urinating) than the standard combination (neostigmine/glycopyrrola…

This study worked with 42 Cherokee citizens to design and test a program that uses community connection and cultural knowledge to help lower blood pressure. The goal was to reduce heart disease risk by combining health education with Cherokee traditions. Researchers measured bloo…

This study tested whether a special belt (Enlight 2100) can help doctors set breathing machine support more accurately for obese patients during surgery. Thirty obese adults having laparoscopic abdominal surgery were included. The goal was to see if the belt works better than sta…

This study looked at how the drug Palynziq, which lowers phenylalanine levels in the blood, affects the brain and thinking abilities in adults with phenylketonuria (PKU). Six participants who were already taking Palynziq underwent brain scans and cognitive tests to measure change…

This study looked at how a night of restricted sleep changes blood flow to the brain in healthy adults. Sixteen men and women had their brain blood flow measured after normal sleep and after limited sleep. Researchers wanted to see if the effect was stronger in men. The goal was …

This study looked at how low oxygen levels (hypoxia) change blood flow in the arms of healthy men and women. Researchers wanted to see if there are sex-related differences in how the nervous system controls blood vessels. The study involved 31 healthy adults aged 18-45 and used a…