Heart stiffness drug shows promise in Insulin-Resistant adults

NCT ID NCT03837626

First seen Sep 30, 2025 · Last updated Apr 25, 2026 · Updated 21 times

Summary

This study tested whether amiloride, a drug that blocks a salt channel in blood vessels, can improve artery stiffness in overweight adults with insulin resistance. 137 men and women (pre- and post-menopausal) participated. The goal was to see if the drug could help control a key risk factor for heart disease.

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Contacts and locations

Locations

  • University of Missouri Hospital and Clinics

    Columbia, Missouri, 65201, United States

Conditions

Explore the condition pages connected to this study.