University Of Missouri-columbia

This study looks at whether eating grape powder can improve gut health and immune function in adults with obesity. Researchers will measure changes in gut bacteria, inflammation, and stress levels. The study involves 50 participants aged 30-45 with a BMI between 30 and 45. Partic…

This study looks at two different surgical methods for fixing a broken bone just above the knee (distal femur fracture). The goal is to see which method helps the bone heal without needing another surgery. About 100 adults who need surgery for this type of break will be randomly …

This study tests whether a daily pill called empagliflozin (a type of SGLT2 inhibitor) can reduce stiffening of arteries that happens with age. The trial will include 80 healthy adults aged 60-80 who have some artery stiffness but no diabetes or major heart disease. Participants …

This study is testing whether a very powerful 7T MRI machine can find tiny brain metastases earlier than standard 1.5T or 3T MRI scans. It involves 20 adults with small-cell lung cancer who have chosen not to receive preventive brain radiation. The goal is to see if the 7T MRI ca…

This study looks at whether antibiotics prevent infections from cat bites on the hand or forearm, and how long they should be taken. About 72 adults who were bitten within the last 24 hours will be randomly assigned to receive either a placebo, a 1-day course, or a 5-day course o…

This study is testing whether whole-body electrical muscle stimulation (WB-EMS) can help adults with neuromuscular diseases like ALS, muscular dystrophy, and myasthenia gravis exercise safely. Because these conditions make normal exercise hard, the WB-EMS suit directly stimulates…

This study tests a brief skills-based program called Show Me FIRST to help teens aged 10-17 with PKU reduce anxiety and depression. 30 participants will be randomly assigned to start the program right away or after a waiting period. The goal is to see if the therapy improves mood…

This study looks at how the nervous system and blood vessels change as women age. Researchers will measure forearm blood flow in 64 women aged 18-70. The goal is to better understand early signs of aging in the body's blood flow system.

This study looks at how getting less sleep than usual affects blood pressure. Researchers will monitor 45 healthy adults, including those with normal weight and obesity, to see changes. The goal is to better understand the connection between sleep and heart health, not to provide…

This study aims to learn more about rare genetic disorders that affect brain development, such as Baker Gordon Syndrome and Syt-1 disorder. Researchers will collect medical data, genetic samples, and imaging from 100 participants (children and adults) to track how these condition…

This study looks at adults who carry the gene for phenylketonuria (PKU) but do not have the disease. Researchers want to see if their brains handle the amino acid phenylalanine differently than people without the gene. Participants will take phenylalanine or a placebo, then under…

This study is collecting blood and bone marrow samples from 50 adults with blood cancers like leukemia. Researchers want to learn how a protein called DPP4 affects these cancers. The goal is to find better, personalized treatments. Participants provide samples but do not receive …

This study aims to find cancer cells and DNA in the blood, urine, and bone marrow of people with solid cancers (like lung, stomach, or colon cancer) and those being screened for lung cancer. By measuring these markers, researchers hope to better understand how cancer spreads and …