University Of California, San Francisco
Clinical trials sponsored by University Of California, San Francisco, explained in plain language.
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Young Adults' blood pressure battle: medication and monitoring test
Disease control TerminatedThis study tested three different blood pressure medications and three different home monitoring approaches for young adults with high blood pressure. Researchers wanted to see which combinations worked best to control blood pressure while also tracking quality of life and side e…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Apr 01, 2026 21:41 UTC
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New drug combo aims to boost immune system against advanced kidney cancer before surgery
Disease control TerminatedThis study tested whether giving a drug called pembrolizumab, with or without another drug called axitinib, before and after surgery could help people with advanced kidney cancer. The goal was to see if this approach could better control the cancer and reduce the chance of it com…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Tiny drops, big hope? device aims to make glaucoma treatment easier
Disease control TerminatedThis study tested a device called Nanodropper that makes eye drops smaller. Researchers wanted to see if using these smaller drops was just as good at lowering eye pressure as using regular-sized drops from the standard bottle. The trial involved 16 adults with stable glaucoma or…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Eye drop vs. pill: race to stop a virus that steals sight
Disease control TerminatedThis study aimed to find the best way to treat a painful and potentially blinding eye infection called cytomegalovirus (CMV) anterior uveitis. It compared an oral antiviral pill (valganciclovir) against an antiviral eye drop (ganciclovir 2%) and a placebo in 51 adults with a conf…
Phase: PHASE2, PHASE3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Asthma Mucus-Buster trial halted early
Disease control TerminatedThis study tested whether a mucus-thinning drug called NAC could improve breathing in adults with moderate-to-severe asthma who had visible mucus plugs in their lungs on CT scans. Participants received either NAC or a placebo for two weeks, then switched. The trial was terminated…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Can simple texts and videos get more people to retest for HIV?
Prevention TerminatedThis study tested 11 different low-cost text and video messages to see which ones best encourage adults at higher risk for HIV to get tested again. It involved 98 people in rural Kenya and Uganda. The goal was to find effective ways to promote regular testing, which helps find ne…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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Clotting drug tested to speed healing after breast cancer surgery
Symptom relief TerminatedThis study tested whether applying a drug called tranexamic acid (TXA) directly to the surgical site could reduce common complications like bleeding and fluid buildup after breast reconstruction surgery following a mastectomy. Each participant acted as their own control, with the…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Can better sleep slow memory loss? new study tests Non-Drug approach
Symptom relief TerminatedThis small pilot study tested whether improving sleep patterns could help people with mild memory problems or early Alzheimer's disease. Researchers developed a program combining bright light therapy and behavioral techniques to regulate daytime and nighttime sleep. They aimed to…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Tourniquet training tested to boost knee recovery
Symptom relief TerminatedThis study tested if adding blood flow restriction training to standard physical therapy helps people recover better after knee cartilage (meniscus) repair surgery. It compared two groups of patients: one using a special cuff during exercises and one using a regular cuff. The mai…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Mar 09, 2026 14:24 UTC
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The 'Missed period Pill' study: could a simple pill offer reproductive choice?
Knowledge-focused TerminatedThis study looked at whether people find it acceptable to use a medication called misoprostol to restart a late period, without first taking a pregnancy test. Researchers enrolled 17 people who had a period that was up to two weeks late and did not want to be pregnant. The goal w…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists hunt for hidden cancer triggers in pregnant Women's environment
Knowledge-focused TerminatedThis study aimed to understand how exposure to chemicals from everyday products and pollution during pregnancy might affect future cancer risks for both mothers and their children. Researchers planned to follow over 1,500 pregnant women and their kids for several years, collectin…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists hunt for hidden triggers behind deadly asthma Flare-Ups
Knowledge-focused TerminatedThis study aimed to discover new causes of severe asthma attacks and better understand how common steroid inhalers work. Researchers analyzed mucus and saliva from 67 adults during a serious asthma episode. The goal was to find clues that could lead to new treatments by studying …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:37 UTC