University Of California, San Francisco
Clinical trials sponsored by University Of California, San Francisco, explained in plain language.
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Young adults with high blood pressure get tailored drug and monitoring test
Disease control TerminatedThis pilot study tested three different blood pressure medicines and three ways for young adults to track their blood pressure at home. The goal was to see which combination works best to lower blood pressure and improve quality of life. The study included 36 people aged 18 to 40…
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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Eye infection breakthrough: new study tests best antiviral approach
Disease control TerminatedThis study compared oral valganciclovir, topical ganciclovir 2%, and placebo for treating CMV anterior uveitis, a viral eye infection that can cause pain, glaucoma, and vision loss. The trial enrolled 51 adults with confirmed CMV in the eye. The goal was to see which treatment be…
Phase: PHASE2, PHASE3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 06, 2026 16:03 UTC
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Immunotherapy before kidney surgery shows promise in small trial
Disease control TerminatedThis study tested giving pembrolizumab (with or without axitinib) before surgery to people with advanced kidney cancer that had spread. The goal was to see if this approach could boost the immune system's attack on the tumor and help control the cancer better than surgery alone. …
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Apr 29, 2026 15:02 UTC
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New rehab trick may boost knee recovery after meniscus surgery
Symptom relief TerminatedThis study looked at whether adding blood flow restriction training to standard physical therapy helps people regain knee strength and muscle size after meniscus repair surgery. About 15 participants were followed for 12 weeks after their operation. The goal was to see if this te…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Tiny drops, big hope: new device may ease glaucoma treatment
Symptom relief TerminatedThis study tested a device called Nanodropper that makes smaller eye drops for people with glaucoma or high eye pressure. The goal was to see if smaller drops work just as well as standard drops to lower eye pressure. The study planned to enroll 16 adults who already use a common…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Asthma mucus treatment study ends early with only 4 volunteers
Symptom relief TerminatedThis study looked at whether a 20% N-acetylcysteine (NAC) solution could improve lung function and reduce mucus in people with moderate-to-severe asthma. Only 4 participants were enrolled before the study was terminated. Each person received both NAC and a placebo in two-week per…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 11, 2026 20:53 UTC
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Could a simple drug stop Post-Surgery bleeding in breast cancer patients?
Symptom relief TerminatedThis study tested if applying tranexamic acid (TXA) directly to the surgical site during breast reconstruction after mastectomy could reduce bleeding (hematomas) and fluid collections (seromas). These complications can delay healing and cancer treatments. The study enrolled 23 wo…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 08, 2026 12:03 UTC
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Pill to bring on late period studied for acceptability
Symptom relief TerminatedThis study tested how acceptable it is to use misoprostol alone to bring on a late period, without first confirming pregnancy. It involved 17 people who were up to 14 days late and did not want to be pregnant. The goal was to see if people were satisfied with this approach and if…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 07, 2026 18:40 UTC
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Sarcoidosis study halted after only 2 patients enrolled
Knowledge-focused TerminatedThis study aimed to see if Acthar gel could improve symptoms and lung function in people with sarcoidosis, a disease that causes inflammation in the lungs. Researchers measured a blood marker called CXCL9 to track the drug's effect. Only 2 people took part before the study was st…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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Can a text or video nudge boost HIV retesting? pilot study aims to find out
Knowledge-focused TerminatedThis pilot study tested several low-cost behavioral nudges—like text messages and videos—to encourage HIV retesting among adults at higher risk of infection in rural Kenya and Uganda. The goal was to see which approaches were acceptable and feasible, and to refine them for a futu…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 16, 2026 23:49 UTC
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Pregnancy pollution link? DREAM study probes cancer risks
Knowledge-focused TerminatedThis study looked at how chemicals in everyday products and the environment might affect cancer risk in pregnant women and their children. Researchers measured chemical levels in the body and checked for signs of inflammation and DNA damage. The study included over 1,500 pregnant…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Scientists probe hidden causes of asthma Flare-Ups
Knowledge-focused TerminatedThis study looked at what causes sudden, severe asthma attacks in adults aged 18 to 75. Researchers measured mucus thickness in patients having an asthma attack to better understand the disease and how inhaled steroids help. The goal was to find new ways to treat asthma, but the …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Light therapy and sleep coaching tested for Alzheimer's prevention
Knowledge-focused TerminatedThis study tested a non-drug program that combined bright light therapy and sleep coaching to improve sleep and thinking in older adults with mild memory problems or early Alzheimer's. Only 15 people took part, and the study was stopped early, so results are limited. The goal was…
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC