Young adults with high blood pressure get new drug comparison

NCT ID NCT05370599

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested three common blood pressure medications—amlodipine, chlorthalidone, and losartan—in 36 young adults aged 18-40 with hypertension. Participants took the drugs at home and monitored their blood pressure regularly. The goal was to see which drug works best and how to improve home monitoring. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

amlodipine, chlorthalidone, or losartan (blood pressure medications)

What this could lead to

If successful, this trial could help identify which blood pressure drug works best for young adults and improve home monitoring strategies.

What could go wrong

This is a small, early pilot study that was terminated, so results may be limited and not generalizable. The drugs have known side effects like dizziness or electrolyte imbalances.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94143, United States