Young adults with high blood pressure get new drug comparison

NCT ID NCT05370599

Terminated Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested three common blood pressure medications—amlodipine, chlorthalidone, and losartan—in 36 young adults aged 18-40 with hypertension. Participants took the drugs at home and monitored their blood pressure regularly. The goal was to see which drug works best and how to improve home monitoring. The study was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: amlodipine, chlorthalidone, or losartan (blood pressure medications)
What this could lead to: If successful, this trial could help identify which blood pressure drug works best for young adults and improve home monitoring strategies.
What could go wrong: This is a small, early pilot study that was terminated, so results may be limited and not generalizable. The drugs have known side effects like dizziness or electrolyte imbalances.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

University of California San Francisco

San Francisco, California, 94143, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.