Could a simple drug cut bleeding after mastectomy?
NCT ID NCT05807074
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether applying tranexamic acid (TXA) directly to the surgical wound during breast removal and reconstruction can reduce bleeding (hematoma) and fluid collections (seroma). These complications can delay healing and cancer treatments. The trial enrolled 23 women at UCSF, but was terminated early, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid (TXA)
- What this could lead to
- If it works, this could offer a simple, low-cost way to reduce common complications after mastectomy and reconstruction.
- What could go wrong
- This was a small, terminated Phase 4 trial with only 23 participants, so results may not be reliable or apply to everyone. TXA can rarely cause blood clots or allergic reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
San Francisco, California, 94143, United States
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