University Of California, Irvine

This study compares two versions of a minimally invasive throat surgery for achalasia, a rare swallowing disorder. Researchers want to see if preserving certain muscle fibers during the procedure reduces acid reflux afterward while still effectively treating the swallowing proble…

This study is testing a new way to care for new mothers who have preeclampsia, a serious pregnancy condition causing high blood pressure. Researchers will use a quick, bedside ultrasound scan to check for fluid buildup in the body. If fluid is found, doctors will give a water pil…

This study aims to see if using special adhesive strips (like Steri-Strips) to close small, simple cuts on the face leads to better patient experiences and less noticeable scars compared to traditional stitches. Researchers will randomly assign 62 adult patients in the emergency …

This study is testing if a short educational video about music for pain, followed by listening to jazz, can help reduce pain for adults waiting in the emergency room with neck or back pain. Researchers will compare this approach to a standard pain management video. The goal is to…

This study aims to see if using an AI chatbot (like ChatGPT) as a supplement to regular therapy can help people feel better. It will enroll 204 adults in the US who are already seeing a therapist for anxiety or depression. Participants will use the chatbot for four weeks, and res…

This is a very early, small study to see if a single dose of two immunotherapy drugs can change the immune cells inside certain stomach and esophageal tumors. It will involve 34 adults with early-stage cancer who have a specific genetic change (ARID1A mutation) and have not had a…